Efectos cardiometabólicos de la pérdida de peso

IF 1.8 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Idoia Genua , Helena Sardà , Antonio Pérez
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引用次数: 0

Abstract

The prevalence of overweight and obesity, and, consequently, associated comorbidities, is increasing significantly worldwide. The guidelines recommend a percentage of weight loss > 5% to achieve beneficial effects on metabolic comorbidities associated with obesity. Furthermore, greater weight losses (> 10%) produce more significant improvements, and may even produce remission of some of these comorbidities. In this chapter, we review the evidence of the effect of weight loss through different strategies (lifestyle intervention, pharmacological treatment, or bariatric surgery) on the main cardiometabolic pathologies associated with excess adipose tissue (type 2 diabetes, high blood pressure, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, inflammation, cardiovascular diseases, and mortality).

减肥对心脏代谢的影响
超重和肥胖症的发病率,以及随之而来的相关并发症,在全球范围内都在显著增加。指南建议,体重减轻 5%,才能对与肥胖相关的代谢并发症产生有益影响。此外,更大的体重减轻(10%)会产生更显著的改善效果,甚至可能使其中一些并发症得到缓解。在本章中,我们将回顾通过不同策略(生活方式干预、药物治疗或减肥手术)减轻体重对与过多脂肪组织相关的主要心脏代谢病症(2 型糖尿病、高血压、血脂异常、代谢功能障碍相关性脂肪肝、炎症、心血管疾病和死亡率)的影响证据。
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来源期刊
Atencion Primaria
Atencion Primaria 医学-医学:内科
CiteScore
2.90
自引率
8.00%
发文量
156
审稿时长
33 days
期刊介绍: Atención Primaria es una revista que publica trabajos de investigación relativos al ámbito de la atención primaria de salud. Desde el punto de vista conceptual, Atención Primaria asume el nuevo modelo de atención primaria de salud, orientado no sólo a la curación de la enfermedad, sino también a su prevención y a la promoción de la salud, tanto en el plano individual como en el de la familia y la comunidad. En estos nuevos aspectos que definen el modelo de atención primaria de salud es en los que se centran los trabajos de investigación que publica Atención Primaria, la primera revista de originales española creada para recoger y difundir la producción científica realizada desde los centros de atención primaria de salud sobre cuestiones como protocolización de la asistencia, programas de prevención, seguimiento y control de pacientes crónicos, organización y gestión de la asistencia primaria, entre otros.
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