Formulation and effectiveness of solid soap preparations from citronella grass (Cymbopogon nardus L.) essential oil extract against Listeria monocytogenes

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES
Lukky Jayadi, Sandry Kesuma, Muhammad Hasan Wattiheluw, Elok Widayanti, Nurma Sabila, Hanandayu Widwiastuti, Riska Yudhistia Asworo, Retno Ikayanti
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引用次数: 0

Abstract

Background: The components of essential oils, such as citronellol, citronellal, and geraniol have been reported to possess the ability to inhibit bacteria. Furthermore, Listeria monocytogenes is a bacteria that often affects humans and its infections can cause meningitis and bacteremia. In pregnant women, Listeria monocytogenes can cause flu-like syndrome with complications of miscarriage, infant death, and meningitis in infants.     Objective: This study evaluated the suitability of solid soap preparations from Citronella grass essential oil, based on its physical properties, such as organoleptic tests, as well as assessments of chemical tests and the effectiveness of the sample produced against bacteria.     Method: The soap-making process was initiated by mixing the fat fraction (stearic acid and coconut oil) with an alkali, namely 30% NaOH. The soap stock was then added to the other ingredients and stirred until it became homogeneous for testing.     Results: The test showed a pH value, water content, total fat, ethanol insoluble material, free fatty acids, chloride content, and unsaponificable fat of 10.8, 14.26, 74.84, 2.4, 0.26, 0.48, and 85.8, respectively. Furthermore, the sample showed a high level of inhibition against Listeria monocytogenes.     Conclusion: Evaluation of citronella essential oil extract soap met the requirements, except for its unsaponifiable fat.
香茅草(Cymbopogon nardus L.)精油提取物固体肥皂制剂的配制及其对李斯特菌的作用
背景:据报道,香茅醇、香茅醛和香叶醇等精油成分具有抑制细菌的能力。此外,李斯特菌是一种经常影响人类的细菌,其感染可导致脑膜炎和菌血症。对孕妇来说,李斯特菌可引起流感样综合征,并发流产、婴儿死亡和婴儿脑膜炎。 研究目的本研究根据香茅草精油的物理特性(如感官测试)、化学测试评估以及所制样品的抑菌效果,对香茅草精油固体肥皂制剂的适用性进行了评估。 方法:肥皂制作过程的第一步是将脂肪部分(硬脂酸和椰子油)与碱(即 30% 的 NaOH)混合。然后将肥皂原液添加到其他配料中,并搅拌至均匀,以便进行测试。 测试结果测试结果显示,pH 值、含水量、总脂肪、乙醇不溶物、游离脂肪酸、氯化物含量和不可皂化脂肪分别为 10.8、14.26、74.84、2.4、0.26、0.48 和 85.8。此外,该样品对李斯特菌也有很高的抑制作用。 结论除不可皂化脂肪外,香茅精油萃取物肥皂的评价符合要求。
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来源期刊
Pharmacy Education
Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-
CiteScore
0.80
自引率
20.00%
发文量
174
期刊介绍: Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.
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