Adherence of HIV/AIDS patients to clinical outcome in Semarang City

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES

Pharmacy Education Pub Date : 2024-04-01 DOI:10.46542/pe.2024.242.1722

Farroh Bintang Sabiti, Thendi Abdul Arief, Nada Aini Sofa, Rendi Adi Saputra, Iga Citra Aryani, Nindita Sari Nastiti, Arvin Faizatun

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引用次数: 0

Abstract

Background: The success of HIV therapy can be measured by clinical, immunological, and virological monitoring. Meanwhile, low adherence to antiretroviral therapy (ART) contributes significantly to the disease progression and emergence of drug-resistant HIV. Objective: This study aimed to determine the correlation between the adherence of HIV/AIDS patients to clinical outcomes in Semarang. Method: This was an observational and cross-sectional approach. The instrument used the Simple Medication Adherence Questionnaire (SMAQ), which was validated and distributed to 50 respondents. The data were analyzed using chi-square (p < 0.05), and the results showed a statistically significant relationship. Result: Respondents were male (96%), aged 26-45 years (76%), high school graduates (24%), working (88%), single (86%), without comorbidity (86%), length of treatment more than 12 months (80%), and general treatment (50%). A total of 31 respondents (62%) adhered to treatment with the combination regimen of Tenofovir/Lamivudine/Efavirenz (20%). There was a significant relationship (p = 0.006) between the length of treatment and patient adherence. The adherence results were not significantly related (p > 0.05) to virological outcomes. Conclusion: There is no significant relationship between the adherence of HIV/AIDS patients and clinical outcomes.

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三宝垄市艾滋病毒/艾滋病患者坚持临床治疗的情况

背景：艾滋病治疗的成功与否可以通过临床、免疫学和病毒学监测来衡量。同时，抗逆转录病毒疗法（ART）的依从性低也是导致疾病进展和耐药性艾滋病出现的重要原因：本研究旨在确定三宝垄地区艾滋病患者坚持治疗与临床结果之间的相关性：方法：这是一项观察性横断面研究。研究工具采用简易用药依从性问卷（SMAQ），该问卷经过验证并分发给 50 名受访者。数据采用卡方（P < 0.05）进行分析，结果显示两者之间存在显著的统计学关系：受访者为男性（96%）、26-45 岁（76%）、高中毕业（24%）、在职（88%）、单身（86%）、无合并症（86%）、治疗时间超过 12 个月（80%）、一般治疗（50%）。共有 31 名受访者（62%）坚持使用替诺福韦/拉米夫定/依非韦伦（20%）联合疗法进行治疗。治疗时间长短与患者的依从性之间存在明显关系（p = 0.006）。坚持治疗的结果与病毒学结果无明显关系（p > 0.05）：艾滋病患者的依从性与临床结果之间没有明显关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

0.80

自引率

20.00%

发文量

174

期刊介绍： Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.