Analysis of the human liver model through semi-analytical and numerical techniques with non-singular kernel.

IF 1.6 4区 医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Akshey, Twinkle R Singh
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引用次数: 0

Abstract

This work consists of the study of the time-fractional human liver model with the Caputo-Fabrizio fractional derivative. The existence and uniqueness of the proposed model are shown using fixed point theory. Also, the stability of the considered model is shown using the Ulam Hyres theorem and the Lyapunov function. The solution of the proposed model is obtained using a semi-analytical and numerical scheme. The series solution obtained from the semi-analytical method gives the proper result at any time, similarly, the numerical scheme gives the solution for a long time. The obtained numerical results are compared with real clinical data and earlier published work and found to be very close to real data than earlier published work. Results in the graphs and tables show that the proposed fractional-order model is superior to the traditional model.

通过半分析和数值技术与非星形核对人体肝脏模型进行分析。
这项工作包括研究具有 Caputo-Fabrizio 分数导数的时间分数人体肝脏模型。利用定点理论证明了所提出模型的存在性和唯一性。此外,还利用乌拉姆海尔定理和 Lyapunov 函数证明了所考虑模型的稳定性。所提模型的解是通过半解析和数值方法获得的。半解析法得到的序列解在任何时候都能给出正确的结果,同样,数值方案也能给出长时间的解。将获得的数值结果与实际临床数据和早期发表的研究成果进行比较,发现与早期发表的研究成果相比,数值结果与实际数据非常接近。图表结果表明,建议的分数阶模型优于传统模型。
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来源期刊
CiteScore
4.10
自引率
6.20%
发文量
179
审稿时长
4-8 weeks
期刊介绍: The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.
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