Virtual and analytical self-expandable braided stent treatment models

IF 1.7 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Reza Abdollahi , Amirali Shahi , Daniel Roy , Simon Lessard , Rosaire Mongrain , Gilles Soulez
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引用次数: 0

Abstract

The Flow Diverter is a self-expandable braided stent that has helped improve the effectiveness of cerebral aneurysm treatment during the last decade. The Flow Diverter's efficiency heavily relies on proper decision-making during the pre-operative phase, which is currently based on static measurements that fail to account for vessel or tissue deformation. In the context of providing realistic measurements, a biomechanical computational method is designed to aid physicians in predicting patient-specific treatment outcomes. The method integrates virtual and analytical treatment models, validated against experimental mechanical tests, and two patient treatment outcomes. In the case of both patients, deployed stent length was one of the validated result parameters, which displayed an error inferior to 1.5% for the virtual and analytical models. These results indicated both models' accuracy. However, the analytical model provided more accurate results with a 0.3% error while requiring a lower computational cost for length prediction. This computational method can offer designing and testing platforms for predicting possible intervention-related complications, patient-specific medical device designs, and pre-operative planning to automate interventional procedures.

虚拟和分析自膨胀编织支架治疗模型
Flow Diverter 是一种可自动扩张的编织支架,在过去十年中帮助提高了脑动脉瘤的治疗效果。分流器的效率在很大程度上取决于术前阶段的正确决策,而目前的决策是基于静态测量,无法考虑血管或组织的变形。为了提供真实的测量结果,我们设计了一种生物力学计算方法,以帮助医生预测特定患者的治疗效果。该方法整合了虚拟和分析治疗模型,并根据实验机械测试和两名患者的治疗结果进行了验证。在这两名患者的病例中,部署支架长度是验证结果参数之一,虚拟模型和分析模型的误差均小于 1.5%。这些结果表明两种模型都很准确。不过,分析模型的结果更准确,误差仅为 0.3%,而长度预测所需的计算成本更低。这种计算方法可以提供设计和测试平台,用于预测可能出现的介入相关并发症、针对患者的医疗设备设计以及术前规划,以实现介入手术的自动化。
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来源期刊
Medical Engineering & Physics
Medical Engineering & Physics 工程技术-工程:生物医学
CiteScore
4.30
自引率
4.50%
发文量
172
审稿时长
3.0 months
期刊介绍: Medical Engineering & Physics provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes. Our focus encompasses the application of the basic principles of physics and engineering to the development of medical devices and technology, with the ultimate aim of producing improvements in the quality of health care.Topics covered include biomechanics, biomaterials, mechanobiology, rehabilitation engineering, biomedical signal processing and medical device development. Medical Engineering & Physics aims to keep both engineers and clinicians abreast of the latest applications of technology to health care.
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