Gut microbe guides alveolar macrophages to fight flu.

Tao Wang, Yanling Wang, Yushi Yao
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Abstract

The intestinal microbiota is associated with defense against respiratory viral infections. In this issue of Cell Host & Microbe, Ngo and colleagues1 show that intestinal commensal segmented filamentous bacteria reprogram alveolar macrophages with improved influenza-viral-neutralizing and phagocytic functions while maintaining inflammatory anergy to better protect the lung.

肠道微生物引导肺泡巨噬细胞对抗流感
肠道微生物群与防御呼吸道病毒感染有关。在本期《细胞宿主与微生物》(Cell Host & Microbe)杂志上,Ngo 及其同事1 的研究表明,肠道共生分节丝状菌对肺泡巨噬细胞进行了重编程,使其具有更好的流感病毒中和功能和吞噬功能,同时保持炎症性过敏,从而更好地保护肺部。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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