Describing Energy Expenditure in Children with a Chronic Disease: A Systematic Review

IF 8 1区医学 Q1 NUTRITION & DIETETICS

Advances in Nutrition Pub Date : 2024-03-01 DOI:10.1016/j.advnut.2024.100198

Bethany Luo , Zoe E. Davidson , Katie O’Brien , Evelyn Volders , Jeffrey Lu , Kali Dunlea , Matisse Lazzari , Natassja Billich , Kay Nguo

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引用次数: 0

Abstract

Understanding energy expenditure in children with chronic disease is critical due to the impact on energy homeostasis and growth. This systematic review aimed to describe available literature of resting (REE) and total energy expenditure (TEE) in children with chronic disease measured by gold-standard methods of indirect calorimetry (IC) and doubly labeled water (DLW), respectively. A literature search was conducted using OVID Medline, Embase, CINAHL Plus, Cochrane, and Scopus until July 2023. Studies were included if the mean age of the participants was ≤18 y, participants had a chronic disease, and measurement of REE or TEE was conducted using IC or DLW, respectively. Studies investigating energy expenditure in premature infants, patients with acute illness, and intensive care patients were excluded. The primary outcomes were the type of data (REE, TEE) obtained and REE/TEE stratified by disease group. In total, 271 studies across 24 chronic conditions were identified. Over 60% of retrieved studies were published >10 y ago and conducted on relatively small population sizes (n range = 1–398). Most studies obtained REE samples (82%) rather than that of TEE (8%), with very few exploring both samples (10%). There was variability in the difference in energy expenditure in children with chronic disease compared with that of healthy control group across and within disease groups. Eighteen predictive energy equations were generated across the included studies. Quality assessment of the studies identified poor reporting of energy expenditure protocols, which may limit the validity of results. Current literature on energy expenditure in children with chronic disease, although extensive, reveals key future research opportunities. International collaboration and robust measurement of energy expenditure should be conducted to generate meaningful predictive energy equations to provide updated evidence that is reflective of emerging disease-modifying therapies.

This study was registered in PROSPERO as CRD42020204690.

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描述慢性病患儿的能量消耗：系统综述。

背景：了解慢性病患儿的能量消耗对能量平衡和生长发育的影响至关重要：了解慢性病患儿的能量消耗对能量平衡和生长的影响至关重要：本系统综述旨在描述分别采用间接量热法（IC）和双标记水法（DLW）这两种金标准方法测量慢性病患儿静息能量消耗（REE）和总能量消耗（TEE）的现有文献：使用 OVID Medline、Embase、CINAHL Plus、Cochrane 和 Scopus 进行文献检索，直至 2023 年 7 月。如果参与者的平均年龄小于 18 岁，参与者患有慢性疾病，并分别使用 IC 或 DLW 测量 REE 或 TEE，则纳入研究。调查早产儿、急性病患者和重症监护患者能量消耗的研究除外。主要结果是获得的数据类型（REE、TEE）以及按疾病组别划分的 REE/TEE 结果：共发现了 271 项研究，涉及 24 种慢性疾病。在检索到的研究中，超过 60% 的研究发表于 10 年前，研究对象规模相对较小（n 范围=1-398）。大多数研究获得的是 REE 样本（82%），而不是 TEE 样本（8%），只有极少数研究同时探索了两种样本（10%）。与健康对照组相比，慢性病患儿的能量消耗在疾病组间和疾病组内存在差异。在纳入的研究中产生了 18 个预测能量方程。研究质量评估发现，能量消耗规程的报告较差，这可能会限制结果的有效性：目前有关慢性病儿童能量消耗的文献虽然很多，但揭示了未来研究的关键机会。应开展国际合作并对能量消耗进行有力的测量，以生成有意义的预测性能量方程，从而提供最新的证据，反映新出现的疾病调整疗法：CRD42020204690。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Nutrition 医学-营养学

CiteScore

17.40

自引率

2.20%

发文量

117

审稿时长

56 days

期刊介绍： Advances in Nutrition (AN/Adv Nutr) publishes focused reviews on pivotal findings and recent research across all domains relevant to nutritional scientists and biomedical researchers. This encompasses nutrition-related research spanning biochemical, molecular, and genetic studies using experimental animal models, domestic animals, and human subjects. The journal also emphasizes clinical nutrition, epidemiology and public health, and nutrition education. Review articles concentrate on recent progress rather than broad historical developments. In addition to review articles, AN includes Perspectives, Letters to the Editor, and supplements. Supplement proposals require pre-approval by the editor before submission. The journal features reports and position papers from the American Society for Nutrition, summaries of major government and foundation reports, and Nutrient Information briefs providing crucial details about dietary requirements, food sources, deficiencies, and other essential nutrient information. All submissions with scientific content undergo peer review by the Editors or their designees prior to acceptance for publication.