A noncoding role of coding mRNA in monogenic olfactory receptor choice.

IF 14.6 1区医学 Q1 NEUROSCIENCES

Trends in Neurosciences Pub Date : 2024-03-01 Epub Date: 2024-02-19 DOI:10.1016/j.tins.2024.02.004

Yue Hao, Kang-Ying Qian, Qian Li

引用次数: 0

Abstract

In a recent study, Pourmorady and colleagues uncovered a noncoding role for olfactory receptor (OR)-coding mRNA in mediating nuclear architecture and singular OR choice. The OR mRNAs reinforce the prevailing enhancer hub and inhibit other competitors, facilitating transition from polygenic to singular OR expression.

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编码 mRNA 在单基因嗅觉受体选择中的非编码作用

在最近的一项研究中，Pourmorady 及其同事发现了嗅觉受体（OR）编码 mRNA 在介导核结构和单一 OR 选择方面的非编码作用。嗅觉受体编码 mRNA 强化了主要的增强子枢纽，抑制了其他竞争者，促进了从多基因到单一嗅觉受体表达的过渡。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Neurosciences 医学-神经科学

CiteScore

26.50

自引率

1.30%

发文量

123

审稿时长

6-12 weeks

期刊介绍： For over four decades, Trends in Neurosciences (TINS) has been a prominent source of inspiring reviews and commentaries across all disciplines of neuroscience. TINS is a monthly, peer-reviewed journal, and its articles are curated by the Editor and authored by leading researchers in their respective fields. The journal communicates exciting advances in brain research, serves as a voice for the global neuroscience community, and highlights the contribution of neuroscientific research to medicine and society.