Neurons in the hypothalamus counteract ageing in mice

IF 28.7 1区医学 Q1 NEUROSCIENCES

Nature Reviews Neuroscience Pub Date : 2024-01-25 DOI:10.1038/s41583-024-00794-1

Joseph Willson

引用次数: 0

Abstract

In mice, a subset of neurons in the dorsomedial hypothalamus control sympathetic nervous system signalling to adipose tissue and are dysregulated with age; activating these neurons prolongs lifespan and slows the decline in physical activity associated with ageing.

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小鼠下丘脑中的神经元能抵御衰老

在小鼠体内，背内侧下丘脑中的一个神经元亚群控制着交感神经系统向脂肪组织发出的信号，并随着年龄的增长而失调；激活这些神经元可延长寿命，并减缓与衰老相关的体力活动下降。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature Reviews Neuroscience NEUROSCIENCES-

自引率

0.60%

发文量

104

期刊介绍： Nature Reviews Neuroscience is a multidisciplinary journal that covers various fields within neuroscience, aiming to offer a comprehensive understanding of the structure and function of the central nervous system. Advances in molecular, developmental, and cognitive neuroscience, facilitated by powerful experimental techniques and theoretical approaches, have made enduring neurobiological questions more accessible. Nature Reviews Neuroscience serves as a reliable and accessible resource, addressing the breadth and depth of modern neuroscience. It acts as an authoritative and engaging reference for scientists interested in all aspects of neuroscience.