Sensory nerve conduction studies in infants, children and teenagers – An update

IF 2 Q3 NEUROSCIENCES

Clinical Neurophysiology Practice Pub Date : 2024-01-01 DOI:10.1016/j.cnp.2024.01.001

Tom Frenzel , Anne-Katrin Baum , Hardy Krause , Christoph Arens , Aiden Haghikia , Imke Galazky

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引用次数: 0

Abstract

Objective

Nerve conduction studies (NCS) in children remain technically challenging and depend on the cooperation of the child. Motor NCS are not compromised by analgosedation but data for sensory NCS are lacking. Here, we ask whether sensory NCS is influenced by analgosedation. We also compare the present data with NCS studies from the 1990s regarding anthropometric acceleration of the contemporary paediatric population.

Methods

Sensory NCS of the median nerve and sural nerve were performed in 182 healthy subjects aged 1 to 18 years during general anaesthesia and in 47 of them without analgosedation.

Results

Sensory NCS was not influenced by midazolam or propofol. The sensory nerve action potential (SNAP) amplitude and the nerve conduction velocity (NCV) of the sural nerve as well as the SNAP of the median nerve show no significant age dependence in age range 1–18 years. The sensory NCV of the median nerve increased age-dependent.

Conclusions

In clinical practice, analgosedation can be used for diagnostic NCS. Sensory NCS data show no relevant secular trend over the last 30 years. Differences due to technical inconsistency predominate.

Significance

Analgosedation can improve diagnostic quality of sensory NCS in children. Additionally, we provide sensory NCS values from a large pediatric cohort.

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婴儿、儿童和青少年的感觉神经传导研究--最新进展

目标儿童神经传导研究（NCS）在技术上仍具有挑战性，并且依赖于儿童的合作。运动神经传导不受镇痛的影响，但感觉神经传导却缺乏相关数据。在此，我们想知道感觉神经NCS是否会受到镇痛的影响。方法对 182 名 1 至 18 岁的健康受试者在全身麻醉期间进行了正中神经和硬脊膜神经的感觉 NCS，其中 47 名受试者在未使用镇痛剂的情况下进行了 NCS。硬神经的感觉神经动作电位（SNAP）振幅和神经传导速度（NCV）以及正中神经的感觉神经动作电位（SNAP）在 1 至 18 岁年龄范围内没有明显的年龄依赖性。结论在临床实践中，镇痛可用于诊断性 NCS。结论在临床实践中，镇痛可用于诊断性 NCS。在过去 30 年中，感觉 NCS 数据未显示出相关的世俗趋势。意义镇痛可提高儿童感觉 NCS 的诊断质量。此外，我们还提供了一个大型儿科队列的感觉 NCS 值。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurophysiology Practice NEUROSCIENCES-

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.