Association between brown sugar intake and decreased risk of cancer in the Amami islands region, Japan.

IF 1.3 4区 医学 Q4 NUTRITION & DIETETICS
Kaede Miyamoto, Tomoko Yasuda, Takumi Akaho, Rie Ibusuki, Ippei Shimoshikiryo, Daisaku Nishimoto, Hironori Miyahara, Kouichi Tokushige, Shiroh Tanoue, Chihaya Koriyama, Toshiro Takezaki
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引用次数: 0

Abstract

Background and objectives: Although excess white sugar intake imposes various health burdens, brown sugar is high in minerals, polyphenols, and polycosanol. However, few epidemiological studies have assessed brown sugar intake for health benefit. People in the Amami islands region, with a relatively high proportion of individuals with longevity, consume brown sugar as a type of refreshment. This cohort study was conducted in Amami to clarify the association of brown sugar intake with mortality risk and cancer incidence.

Methods and study design: Participants were recruited from the general population of Amami as part of the Japan Multi-Institutional Collaborative Cohort Study. The number of eligible participants was 5004 (2057 men and 2947 women). During the median follow-up period of 13.4 years, 274 deaths and 338 cases of cancer were observed. HRs and 95% CIs were estimated using the Cox proportional hazard model, after adjusting for sugar-related and other variables.

Results: After adjusting for their related confounding factors, brown sugar intake was associated with decreased HRs and a decreasing trend for all-site and stomach cancer incidence (p = 0.001 and 0.017, respectively) in women and men, and for breast cancer incidence (p = 0.034) in women. Additionally, a decreasing trend in the HRs for lung cancer incidence was observed among never and ex-smokers (p = 0.039). Decreased HRs for overall death, cancer, and cardiovascular disease were not apparent.

Conclusions: Brown sugar intake was associated with decreased risk of all-site, stomach, and breast cancer incidences in the Amami population.

日本奄美群岛地区红糖摄入量与癌症风险降低之间的关系。
背景和目的:虽然过量摄入白糖会对健康造成各种负担,但红糖含有大量矿物质、多酚和多元糖醇。然而,很少有流行病学研究评估红糖摄入对健康的益处。奄美群岛地区的长寿人口比例相对较高,他们将红糖作为一种茶点食用。这项队列研究在奄美岛进行,旨在明确红糖摄入量与死亡风险和癌症发病率之间的关系:作为日本多机构协作队列研究的一部分,研究人员从奄美的普通人群中招募。符合条件的参与者有 5004 人(男性 2057 人,女性 2947 人)。在中位 13.4 年的随访期间,共观察到 274 例死亡和 338 例癌症病例。在对与糖有关的变量和其他变量进行调整后,使用 Cox 比例危险模型估算了 HRs 和 95% CIs:结果:在调整了相关混杂因素后,红糖摄入量与女性和男性全部位癌症和胃癌发病率(p = 0.001 和 0.017,分别为 0.001 和 0.017)以及女性乳腺癌发病率(p = 0.034)的 HRs 下降和下降趋势相关。此外,在从不吸烟者和戒烟者中,肺癌发病率的 HRs 呈下降趋势(p = 0.039)。总体死亡、癌症和心血管疾病的死亡率下降趋势并不明显:结论:在奄美人中,红糖摄入量与所有部位癌症、胃癌和乳腺癌发病风险的降低有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.50
自引率
7.70%
发文量
58
审稿时长
6-12 weeks
期刊介绍: The aims of the Asia Pacific Journal of Clinical Nutrition (APJCN) are to publish high quality clinical nutrition relevant research findings which can build the capacity of clinical nutritionists in the region and enhance the practice of human nutrition and related disciplines for health promotion and disease prevention. APJCN will publish original research reports, reviews, short communications and case reports. News, book reviews and other items will also be included. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by at least two anonymous reviewers and the Editor. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as material cannot be returned. Final acceptance or rejection rests with the Editorial Board
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