The relation between neuroimaging and visual impairment in children and adolescents with cerebral palsy: A systematic review

IF 1.4 4区医学 Q4 CLINICAL NEUROLOGY

Brain & Development Pub Date : 2023-11-27 DOI:10.1016/j.braindev.2023.11.002

Monica Crotti , Sarah Genoe , Nofar Ben Itzhak , Lisa Mailleux , Els Ortibus

{"title":"The relation between neuroimaging and visual impairment in children and adolescents with cerebral palsy: A systematic review","authors":"Monica Crotti , Sarah Genoe , Nofar Ben Itzhak , Lisa Mailleux , Els Ortibus","doi":"10.1016/j.braindev.2023.11.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p><span><span>The structure–function relation between magnetic resonance imaging (MRI) and visual impairment (VI) in children with </span>cerebral palsy (CP) has not been fully unravelled. The present </span>systematic review<span> aims to summarize the relation between brain lesions on MRI and VI in children and adolescents with CP.</span></p></div><div><h3>Methods</h3><p>PubMed, Embase, Web of Science Core Collection, and Cochrane Database were systematically searched according to the PRISMA checklist. A total of 45 articles met the inclusion criteria.</p></div><div><h3>Results</h3><p><span>White matter lesions<span> were most frequently associated with VI. Only 25 studies described lesions within specific structures, mainly in the optic radiations. Only four studies reported on the </span></span>thalamus<span>. 8.4% of children with CP showed no brain abnormalities<span> on MRI. Diffusion-weighted MRI studies showed that decreased structural connectivity in the optic radiations, superior longitudinal fasciculus<span><span>, posterior limb of the internal capsule, and </span>occipital lobe is associated with more severe VI.</span></span></span></p></div><div><h3>Conclusions</h3><p>All types of brain lesions lead to visual dysfunctions, arguing for a comprehensive visual assessment in all children with CP. Whereas white matter damage is a well-known contributor, the exact contribution of specific visual structures requires further investigation, to enable early prediction, detection, and intervention.</p></div>","PeriodicalId":56137,"journal":{"name":"Brain & Development","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Brain & Development","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0387760423001729","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective

The structure–function relation between magnetic resonance imaging (MRI) and visual impairment (VI) in children with cerebral palsy (CP) has not been fully unravelled. The present systematic review aims to summarize the relation between brain lesions on MRI and VI in children and adolescents with CP.

Methods

PubMed, Embase, Web of Science Core Collection, and Cochrane Database were systematically searched according to the PRISMA checklist. A total of 45 articles met the inclusion criteria.

Results

White matter lesions were most frequently associated with VI. Only 25 studies described lesions within specific structures, mainly in the optic radiations. Only four studies reported on the thalamus. 8.4% of children with CP showed no brain abnormalities on MRI. Diffusion-weighted MRI studies showed that decreased structural connectivity in the optic radiations, superior longitudinal fasciculus, posterior limb of the internal capsule, and occipital lobe is associated with more severe VI.

Conclusions

All types of brain lesions lead to visual dysfunctions, arguing for a comprehensive visual assessment in all children with CP. Whereas white matter damage is a well-known contributor, the exact contribution of specific visual structures requires further investigation, to enable early prediction, detection, and intervention.

Abstract Image

查看原文本刊更多论文

儿童和青少年脑瘫患者神经影像学与视力损害的关系:一项系统综述。

目的:磁共振成像(MRI)与脑瘫(CP)患儿视力损害(VI)的结构-功能关系尚未完全阐明。本系统综述旨在总结儿童和青少年cp的MRI脑病变与VI的关系。方法:根据PRISMA检查表系统检索PubMed、Embase、Web of Science Core Collection和Cochrane数据库。共有45篇文章符合纳入标准。结果:白质病变最常与VI相关。只有25项研究描述了特定结构内的病变，主要是视界辐射。只有四项研究报告了丘脑。8.4%的CP患儿MRI未见脑异常。弥散加权MRI研究显示，视神经辐射、上纵束、内囊后肢和枕叶结构连通性下降与更严重的vi相关。所有类型的脑部病变都会导致视觉功能障碍，因此需要对所有CP患儿进行全面的视觉评估。尽管白质损伤是众所周知的因素，但具体视觉结构的确切影响需要进一步调查，以便早期预测、检测和干预。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Brain & Development 医学-临床神经学

CiteScore

3.60

自引率

0.00%

发文量

153

审稿时长

50 days

期刊介绍： Brain and Development (ISSN 0387-7604) is the Official Journal of the Japanese Society of Child Neurology, and is aimed to promote clinical child neurology and developmental neuroscience. The journal is devoted to publishing Review Articles, Full Length Original Papers, Case Reports and Letters to the Editor in the field of Child Neurology and related sciences. Proceedings of meetings, and professional announcements will be published at the Editor''s discretion. Letters concerning articles published in Brain and Development and other relevant issues are also welcome.