{"title":"Optimisation of seed oil and powder of Momordica charantia in the formulation of body scrub cream","authors":"Lina Winarti, Shifwatu Dzakkiyah, Eka Deddy Irawan, Erlia Narulita","doi":"10.46542/pe.2023.234.127131","DOIUrl":null,"url":null,"abstract":"Background: Momordica charantia seed oil and powder are potential ingredients for a body scrub. The seeds contain fatty acids to moisturise the skin, and the mineral content to remove dead skin cells and nourish the skin. Objective: To determine the optimal efficiency of Momordica charantia seed oil and powder on body scrub cream produce. Methods: The body scrub used W/O (water-in-Oil) cream base. Simplex Lattice Design was used to determine five formulas. The irritation test with the Draize Skin Test method was carried out on rats (n = three, in each formula), and the Primary Dermal Irritation Index (PDII) was calculated. Informed consent from the female participants has been obtained for the hedonic test. Results: The body scrub cream produced appropriate organoleptic, was not irritating, and was stable after centrifugation and cycling test. The optimum formula contained five grams of oil and one gram of powder with a pH of 5.21; viscosity of 205.33 dPa.s; spreading of 6.12cm; adhesion time of 19.86 seconds; rate of washing of 20.60 seconds; a colour value of 4.04; scent value of 2.90; and texture value of 2.98. Conclusion: The optimised body scrub cream yielded a good formula which can be developed as a body scrub preparation.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":"23 1","pages":"0"},"PeriodicalIF":0.5000,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacy Education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46542/pe.2023.234.127131","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EDUCATION, SCIENTIFIC DISCIPLINES","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Momordica charantia seed oil and powder are potential ingredients for a body scrub. The seeds contain fatty acids to moisturise the skin, and the mineral content to remove dead skin cells and nourish the skin. Objective: To determine the optimal efficiency of Momordica charantia seed oil and powder on body scrub cream produce. Methods: The body scrub used W/O (water-in-Oil) cream base. Simplex Lattice Design was used to determine five formulas. The irritation test with the Draize Skin Test method was carried out on rats (n = three, in each formula), and the Primary Dermal Irritation Index (PDII) was calculated. Informed consent from the female participants has been obtained for the hedonic test. Results: The body scrub cream produced appropriate organoleptic, was not irritating, and was stable after centrifugation and cycling test. The optimum formula contained five grams of oil and one gram of powder with a pH of 5.21; viscosity of 205.33 dPa.s; spreading of 6.12cm; adhesion time of 19.86 seconds; rate of washing of 20.60 seconds; a colour value of 4.04; scent value of 2.90; and texture value of 2.98. Conclusion: The optimised body scrub cream yielded a good formula which can be developed as a body scrub preparation.
期刊介绍:
Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.