Ergogenic properties, safety evaluation and regulations of selected ingredients in testosterone booster dietary supplements

IF 5.3 2区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Food Reviews International Pub Date : 2023-10-16 DOI:10.1080/87559129.2023.2238055

Karol Jędrejko, Artemii Lazarev, Maciej Jędrejko, Bożena Muszyńska

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Abstract

Testosterone boosters (TB) are multi-ingredient dietary supplements that have gained popularity among athletes and the general population. However, certain ingredients in TB are associated with adverse events. The aim of the present study was to analyze dietary TB supplements available for sale online on shop.bodybuilding.com and amazon.com in ten distribution area markets. We evaluated the top five best-selling TB and the most frequently used ingredients of 50 selected TB and the evidence for their efficacy and safety, as well as legislation, statements in the European Union (EU) and sports organizations such as International Olympic Committee (IOC), International Society of Sports Nutrition (ISSN), Australian Institute of Sport (AIS) and World Anti- Doping Agency (WADA). Among 50 TB, 361 components and 98 ingredients were identified. The following ingredients were included in the final review: fenugreek, D- aspartic acid (DAA), 3,3′-diindolylmethane (DIM) or indole-3-carbinol (I3C), Eurycoma longifolia, Cordyceps spp., and ecdysteroids. In EU an authorized health claims refer to few ingredients in TB, mainly minerals, vitamins. Some ingredients were recognized by international sports organizations such as the ISSN, AIS, and WADA and some were identified as unauthorized ingredients/novel food in the EU. Selected ingredients can possibly increase the risk of endocrine system dysregulation.

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睾酮促进剂膳食补充剂中选定成分的人体原性、安全性评价和法规

睾酮助推器(TB)是一种多成分膳食补充剂，在运动员和普通人群中很受欢迎。然而，结核病中的某些成分与不良事件有关。本研究的目的是分析shop.bodybuilding.com和amazon.com在10个分销区域市场上在线销售的膳食结核病补充剂。我们评估了前五名最畅销的结核病和50种选定结核病中最常用的成分及其有效性和安全性的证据，以及欧盟(EU)和国际奥委会(IOC)、国际运动营养学会(ISSN)、澳大利亚体育研究所(AIS)和世界反兴奋剂机构(WADA)等体育组织的立法、声明。在50 TB中鉴定出361种成分和98种成分。最终审查的成分包括胡芦巴、D-天冬氨酸(DAA)、3,3 ' -二吲哚甲烷(DIM)或吲哚-3-甲醇(I3C)、长叶Eurycoma longifolia、冬虫夏草和外皮甾体。在欧盟，一项授权的健康声明指的是结核病中的少数成分，主要是矿物质和维生素。一些成分被国际体育组织(ISSN)、国际体育协会(AIS)、世界反兴奋剂组织(WADA)等认可，一些成分在欧盟被认定为未经授权的成分/新食品。某些成分可能会增加内分泌系统失调的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Food Reviews International 工程技术-食品科技

CiteScore

11.50

自引率

1.70%

发文量

127

审稿时长

>24 weeks

期刊介绍： Food Reviews International presents state-of-the-art reviews concerned with food production, processing, acceptability, and nutritional values—examining the relationship of food and nutrition to health, as well as the differing problems affecting both affluent and developing nations. Offering technical solutions to critical global food dilemmas and shortages, Food Reviews International contains articles of interest for: •food scientists and technologists •food and cereal chemists •chemical engineers •agriculturists •microbiologists •toxicologists •nutritionists