High-performance microelectrode of PEDOT/Pt-black for low voltage neurostimulaiton

K. Yamaguchi, Masanori Tanaka, S. Yamagiwa, H. Sawahata, R. Numano, M. Ishida, T. Kawano
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引用次数: 2

Abstract

Here we report a material for low-voltage and micro-scale electrode stimulation, that combines high charge injecting and low impedance characteristics of poly (3, 4-ethylenedioxythiophene) (PEDOT) with a large effective surface area by using a platform of platinum black (Pt-black). The layer-by-layer assembled PEDOT/Pt-black electrode with the diameter of 30 μm exhibits the charge-injection delivery capacity (QCDC) is 684 mC/cm2, which is 1.6 times value of the same-sized Pt-black electrode. In vivo animal experiments confirm that the 8-μm-diameter PEDOT/Pt-black electrode enables the electrical stimulation of mouse's nerves with the voltage of 400 mV, which value is lower than conventional electrodes. The proposed small diameter and high QCDC electrode potentially offers powerful applications, including low voltage stimulation and stimulations of individual neurons in which the cell body has a diameter of ~10 μm.
用于低压神经刺激的高性能PEDOT/Pt-black微电极
本文报道了一种用于低压和微尺度电极刺激的材料,该材料结合了聚(3,4 -乙烯二氧噻吩)(PEDOT)的高电荷注入和低阻抗特性,具有大的有效表面积,使用铂黑(Pt-black)平台。直径为30 μm的PEDOT/Pt-black电极的电荷注入输送能力(QCDC)为684 mC/cm2,是相同尺寸Pt-black电极的1.6倍。动物体内实验证实,直径为8 μm的PEDOT/Pt-black电极对小鼠神经的电刺激电压为400 mV,低于常规电极。所提出的小直径和高QCDC电极具有潜在的强大应用,包括低电压刺激和刺激单个神经元,其中细胞体直径为~10 μm。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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