Simulating fluid flow in “Shrinky Dink” microfluidic chips — Potential for combination with low-cost DIY microPIV

Andrija Jovic, Ž. Janićijević, M. Janković, Novica Z. Janković, Marko Barjaktarovic, E. S. Cantrak, I. Gadjanski
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引用次数: 1

Abstract

This paper describes the first steps towards a union of low-cost “Shrinky Dink” (SD) microfluidic chip fabrication with low-cost do-it-yourself (DIY) micro-PIV. The SD microfluidic chip fabrication technique enables rapid development of complex designs using inexpensive materials and reagents, while abrogating the need for a cleanroom. DIY microPIV system provides a low-cost means of accurate flow profile analysis in microchannels, comparable to high-cost, standard microPIV setups. Initially, a simple microfluidic design of a T-junction was created and several chips with the same design were fabricated by the SD technique. We used COMSOL Multiphysics Creeping Flow interface to simulate the flow profiles in the obtained channel geometry. The next step will be to experimentally verify these simulations using our DIY microPIV system, in order to confirm the potential of combined use of these two cost-effective systems, to rapidly produce and analyze microfluidic designs, thereby enabling greater accessibility to these methods in labs with limited resources. It is envisioned that the systems described here can be effectively employed for a wide array of applications in biophysics, fluid mechanics, and bioengineering.
在“Shrinky Dink”微流控芯片中模拟流体流动-与低成本DIY microPIV结合的潜力
本文描述了低成本“Shrinky Dink”(SD)微流控芯片制造与低成本DIY (DIY)微型piv结合的第一步。SD微流控芯片制造技术可以使用廉价的材料和试剂快速开发复杂的设计,同时取消了对洁净室的需要。DIY microPIV系统提供了一种低成本的方法,可以在微通道中进行精确的流动剖面分析,可与高成本的标准microPIV设置相媲美。首先,创建了一个简单的t型结微流控设计,并通过SD技术制造了几个具有相同设计的芯片。我们使用COMSOL Multiphysics蠕变流界面来模拟获得的通道几何形状中的流动剖面。下一步将使用我们的DIY microPIV系统进行实验验证这些模拟,以确认这两种具有成本效益的系统组合使用的潜力,以快速生产和分析微流体设计,从而使这些方法在资源有限的实验室中更容易获得。可以设想,这里描述的系统可以有效地用于生物物理学、流体力学和生物工程的广泛应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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