COVID-19大流行期间抗微生物药物耐药性的系统综述

Q4 Medicine
Janice S W Burnside, Opal Vanessa Buchthal, Uday Patil
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引用次数: 0

摘要

耐抗生素病原体,或“超级细菌”,每年在美国造成3.5万多人死亡和280多万例耐抗生素感染。在世界范围内,抗微生物药物耐药性每年至少夺去70万人的生命,其中23万人死于耐多药结核病。预计到2050年,与抗菌素耐药性有关的死亡人数将增加到1 000万。杀菌剂的使用、针对病毒感染的抗生素处方不当、住院时间延长以及其他问题都会导致抗生素耐药性。本研究的目的是确定COVID-19大流行是否对全球AMR率产生了影响。虽然研究结果还为时尚早,但有4篇文章表明增加了,2篇文章发现减少了,2篇文章的结果好坏参半。这次大流行可能会导致耐药感染的增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Systematic Review of Antimicrobial Resistance During the COVID-19 Pandemic.

Antimicrobial-resistant pathogens, or "superbugs," cause more than 35 000 deaths and more than 2.8 million antibiotic-resistant infections in the US each year. Worldwide, antimicrobial resistance (AMR) has claimed at least 700 000 lives per year, including 230 000 from multi-drug resistant (MDR) tuberculosis. AMR-related deaths are projected to increase to 10 million by the year 2050. The use of biocides, improper prescribing of antibiotics for viral infections, prolonged hospital stays, and other issues contribute to AMR. The purpose of this study was to determine whether the COVID-19 pandemic has had an impact on the rates of AMR globally. While it is still early for the results of research studies, 4 articles indicated an increase, 2 found a decrease, and 2 had mixed results. It is possible that this pandemic may be contributing to an increase of medication-resistant infections.

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