自杀性摄入专业溶索仿®导致延迟死亡的内脏显微模式。

Q4 Medicine
Stefano Tambuzzi, Guendalina Gentile, Salvatore Andreola, Arnaldo Stanislao Migliorini, Riccardo Zoja
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引用次数: 1

摘要

溶菌素®在专业洗涤剂的配方中被广泛应用于多个领域,而它的自杀摄入是不寻常的。因此,这种致命中毒的生物学迹象仍然不清楚和难以捉摸,类似于其主要成分苯扎氯铵(BZK)引起的组织学病变。此外,由于文献中报道的所有死亡都是立即发生的,因此迄今为止从未报道过BZK在长期存活的受试者中致命毒性的显微镜照片。具体来说,这篇简短的通讯报道了一名妇女服用专业溶索仿®自杀的独特案例,她在两周后死亡。尸检显示局部或全身的腐蚀性食入迹象;此外,组织学分析显示肺、心脏和肾脏有明显的细胞损伤。在我们的案例中,毒理学调查没有被授权,因为它们不再被认为是重要的。因此,在这一框架下,组织学检查在调查和证明BZK的系统性传播所造成的致命影响方面发挥了根本作用,否则就无法对这种致命影响进行调查。因此,在长期生存的物质中毒病例中,法医毒理学调查可能不再可能或可行,组织学检查可能是成功观察和证明其致命影响的唯一资源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Visceral Microscopic Pattern From Suicidal Ingestion of Professional Lysoform® With Delayed Death.

Lysoform® in the formulation of professional detergent is widely used in several fields, whereas its suicidal ingestion is an unusual occurrence. Therefore, the biological signs of this fatal poisoning remain unclear and elusive, similarly to the histological lesions induced by its main constituent, which is benzalkonium chloride (BZK). Furthermore, since all the deaths that has been reported in the literature occurred immediately, microscopic pictures of BZK lethal toxicity in subjects with prolonged survival have never been reported to date. Specifically, this brief communication reports the unique case of a woman who ingested professional Lysoform® to commit suicide, for which she died two weeks later. The autopsy examination showed either local or systemic signs of caustic ingestion; moreover, the histological analysis showed clear cellular damage of lungs, heart, and kidneys. In our case, toxicological investigations were not authorized as they were no longer considered significant. In this framework, the histological examination has therefore assumed a fundamental role in investigating and demonstrating the lethal effects caused by the systemic dissemination of BZK, which would otherwise no longer be investigable. Therefore, in cases of substance intoxication with prolonged survival where forensic toxicological investigations may be no longer possible or feasible, the histological examination may be the only resource to successfully observe and demonstrate its lethal effects.

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来源期刊
Academic Forensic Pathology
Academic Forensic Pathology Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
13
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