Sabrina L Begley, Timothy G White, Kevin A Shah, Justin Turpin, Daniel Toscano, Amir R Dehdashti, Ina Teron, Thomas Link, Athos Patsalides, Henry H Woo
{"title":"血管内线圈系统治疗颅内小动脉瘤的比较。","authors":"Sabrina L Begley, Timothy G White, Kevin A Shah, Justin Turpin, Daniel Toscano, Amir R Dehdashti, Ina Teron, Thomas Link, Athos Patsalides, Henry H Woo","doi":"10.1177/15910199231182456","DOIUrl":null,"url":null,"abstract":"<p><p>BackgroundEndovascular coiling of small, intracranial aneurysms remains controversial and difficult, despite advances in technology.MethodsWe retrospectively reviewed data for 62 small aneurysms (<3.99 mm) in 59 patients. Occlusion rates, complications rates, and coil packing densities were compared between subgroups based upon coil type and rupture status.ResultsRuptured aneurysms predominated (67.7%). Aneurysms measured 2.99 ± 0.63 mm by 2.51 ± 0.61 mm with an aspect ratio of 1.21 ± 0.34 mm. Brands included Optima (Balt) (29%), MicroVention Hydrogel (24.2%), and Penumbra SMART (19.4%) coil systems. Average packing density was 34.3 ± 13.5 mm<sup>3</sup>. Occlusion rate was 100% in unruptured aneurysms; 84% utilized adjuvant devices. For ruptured aneurysms, complete occlusion or stable neck remnant was achieved in 88.6% while recanalization occurred in 11.4%. No rebleeding occurred. Average packing density (<i>p</i> = 0.919) and coil type (<i>p</i> = 0.056) did not impact occlusion. Aspect ratio was smaller in aneurysms with technical complications (<i>p</i> = 0.281), and aneurysm volume was significantly smaller in those with coil protrusion (<i>p</i> = 0.018). Complication rates did not differ between ruptured and unruptured aneurysms (22.6 vs. 15.8%, <i>p</i> = 0.308) or coil types (<i>p</i> = 0.830).ConclusionDespite advances in embolization devices, coiling of small intracranial aneurysms is still scrutinized. High occlusion rates are achievable, especially in unruptured aneurysms, with coil type and packing density suggesting association with complete occlusion. Technical complications may be influenced by aneurysm geometry. Advances in endovascular technologies have revolutionized small aneurysm treatment, with this series demonstrating excellent aneurysm occlusion especially in unruptured aneurysms.</p>","PeriodicalId":14380,"journal":{"name":"Interventional Neuroradiology","volume":" ","pages":"690-696"},"PeriodicalIF":2.1000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12475379/pdf/","citationCount":"0","resultStr":"{\"title\":\"A comparison of endovascular coil systems for the treatment of small intracranial aneurysms.\",\"authors\":\"Sabrina L Begley, Timothy G White, Kevin A Shah, Justin Turpin, Daniel Toscano, Amir R Dehdashti, Ina Teron, Thomas Link, Athos Patsalides, Henry H Woo\",\"doi\":\"10.1177/15910199231182456\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>BackgroundEndovascular coiling of small, intracranial aneurysms remains controversial and difficult, despite advances in technology.MethodsWe retrospectively reviewed data for 62 small aneurysms (<3.99 mm) in 59 patients. Occlusion rates, complications rates, and coil packing densities were compared between subgroups based upon coil type and rupture status.ResultsRuptured aneurysms predominated (67.7%). Aneurysms measured 2.99 ± 0.63 mm by 2.51 ± 0.61 mm with an aspect ratio of 1.21 ± 0.34 mm. Brands included Optima (Balt) (29%), MicroVention Hydrogel (24.2%), and Penumbra SMART (19.4%) coil systems. Average packing density was 34.3 ± 13.5 mm<sup>3</sup>. Occlusion rate was 100% in unruptured aneurysms; 84% utilized adjuvant devices. For ruptured aneurysms, complete occlusion or stable neck remnant was achieved in 88.6% while recanalization occurred in 11.4%. No rebleeding occurred. Average packing density (<i>p</i> = 0.919) and coil type (<i>p</i> = 0.056) did not impact occlusion. Aspect ratio was smaller in aneurysms with technical complications (<i>p</i> = 0.281), and aneurysm volume was significantly smaller in those with coil protrusion (<i>p</i> = 0.018). Complication rates did not differ between ruptured and unruptured aneurysms (22.6 vs. 15.8%, <i>p</i> = 0.308) or coil types (<i>p</i> = 0.830).ConclusionDespite advances in embolization devices, coiling of small intracranial aneurysms is still scrutinized. High occlusion rates are achievable, especially in unruptured aneurysms, with coil type and packing density suggesting association with complete occlusion. Technical complications may be influenced by aneurysm geometry. Advances in endovascular technologies have revolutionized small aneurysm treatment, with this series demonstrating excellent aneurysm occlusion especially in unruptured aneurysms.</p>\",\"PeriodicalId\":14380,\"journal\":{\"name\":\"Interventional Neuroradiology\",\"volume\":\" \",\"pages\":\"690-696\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12475379/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Interventional Neuroradiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1177/15910199231182456\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/6/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Interventional Neuroradiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/15910199231182456","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/6/13 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
背景:尽管技术进步,颅内小动脉瘤的血管卷曲仍然存在争议和困难。方法回顾性分析62例小动脉瘤(3例)的临床资料。未破裂动脉瘤的闭塞率为100%;84%使用辅助器械。对于破裂的动脉瘤,88.6%的患者实现了完全闭塞或稳定的颈部残余,11.4%的患者实现了再通。无再出血发生。平均填充密度(p = 0.919)和线圈类型(p = 0.056)对闭塞无影响。有技术并发症的动脉瘤宽高比较小(p = 0.281),有线圈突出的动脉瘤体积较小(p = 0.018)。并发症发生率在破裂动脉瘤和未破裂动脉瘤(22.6 vs 15.8%, p = 0.308)或动脉瘤圈类型(p = 0.830)之间没有差异。结论尽管栓塞装置有了进步,颅内小动脉瘤的栓塞仍需仔细检查。高闭塞率是可以实现的,特别是在未破裂的动脉瘤中,线圈类型和填充密度提示与完全闭塞有关。技术性并发症可能受动脉瘤几何形状的影响。血管内技术的进步使小动脉瘤治疗发生了革命性的变化,这一系列的研究表明,在未破裂的动脉瘤中,动脉瘤的闭塞效果非常好。
A comparison of endovascular coil systems for the treatment of small intracranial aneurysms.
BackgroundEndovascular coiling of small, intracranial aneurysms remains controversial and difficult, despite advances in technology.MethodsWe retrospectively reviewed data for 62 small aneurysms (<3.99 mm) in 59 patients. Occlusion rates, complications rates, and coil packing densities were compared between subgroups based upon coil type and rupture status.ResultsRuptured aneurysms predominated (67.7%). Aneurysms measured 2.99 ± 0.63 mm by 2.51 ± 0.61 mm with an aspect ratio of 1.21 ± 0.34 mm. Brands included Optima (Balt) (29%), MicroVention Hydrogel (24.2%), and Penumbra SMART (19.4%) coil systems. Average packing density was 34.3 ± 13.5 mm3. Occlusion rate was 100% in unruptured aneurysms; 84% utilized adjuvant devices. For ruptured aneurysms, complete occlusion or stable neck remnant was achieved in 88.6% while recanalization occurred in 11.4%. No rebleeding occurred. Average packing density (p = 0.919) and coil type (p = 0.056) did not impact occlusion. Aspect ratio was smaller in aneurysms with technical complications (p = 0.281), and aneurysm volume was significantly smaller in those with coil protrusion (p = 0.018). Complication rates did not differ between ruptured and unruptured aneurysms (22.6 vs. 15.8%, p = 0.308) or coil types (p = 0.830).ConclusionDespite advances in embolization devices, coiling of small intracranial aneurysms is still scrutinized. High occlusion rates are achievable, especially in unruptured aneurysms, with coil type and packing density suggesting association with complete occlusion. Technical complications may be influenced by aneurysm geometry. Advances in endovascular technologies have revolutionized small aneurysm treatment, with this series demonstrating excellent aneurysm occlusion especially in unruptured aneurysms.
期刊介绍:
Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...