Rodrigo Cunha Oliveira, Juliana Sacramento Mota de Souza, Luiz Carlos Júnior Alcântara, Monick Lindenmeyer Guimarães, Carlos Brites, Joana Paixão Monteiro-Cunha
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引用次数: 0
摘要
在巴西南部,半数以上的感染者与 HIV-1 亚型 C 有关,而在巴西其他地区,该亚型 C 的感染率也在不断上升。我们之前在巴西东北部进行的一项研究发现,C 亚型的感染率为 4.1%。这项研究根据五个新的病毒序列,调查了巴伊亚州 C 亚型的起源。系统发生学分析表明,巴伊亚州发现的 C 亚型病毒来自在巴西其他地区流行的主系。
Molecular and Phylogenetic Analysis of HIV-1 Subtype C in Bahia State, Northeastern Brazil.
HIV-1 subtype C is associated with more than half of infections in southern Brazil and has been increasing in other regions of the country. In a previous study carried out in northeastern Brazil, we found a prevalence of 4.1% of subtype C. This work investigates the origin of subtype C in the state of Bahia based on five new viral sequences. The phylogenetic analysis showed that subtype C viruses found in Bahia descend from the main lineage that circulates in other Brazilian regions.
期刊介绍:
AIDS Research and Human Retroviruses was the very first AIDS publication in the field over 30 years ago, and today it is still the critical resource advancing research in retroviruses, including AIDS. The Journal provides the broadest coverage from molecular biology to clinical studies and outcomes research, focusing on developments in prevention science, novel therapeutics, and immune-restorative approaches. Cutting-edge papers on the latest progress and research advances through clinical trials and examination of targeted antiretroviral agents lead to improvements in translational medicine for optimal treatment outcomes.
AIDS Research and Human Retroviruses coverage includes:
HIV cure research
HIV prevention science
- Vaccine research
- Systemic and Topical PreP
Molecular and cell biology of HIV and SIV
Developments in HIV pathogenesis and comorbidities
Molecular biology, immunology, and epidemiology of HTLV
Pharmacology of HIV therapy
Social and behavioral science
Rapid publication of emerging sequence information.