评估 SYNTAX-II 评分对急性冠状动脉综合征患者不良心脏事件和临床预后的预测价值。

IF 2.6 3区 医学 Q2 PERIPHERAL VASCULAR DISEASE
Angiology Pub Date : 2024-09-01 Epub Date: 2023-06-09 DOI:10.1177/00033197231181958
Yasin Yuksel, Cennet Yildiz, Sennur Kose
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引用次数: 0

摘要

预后信息对于急性冠状动脉综合征(ACS)的治疗非常重要。我们的目的是评估 PCI 与 Taxus 和心脏手术(SYNTAX)之间的协同作用评分-II(SSII),以预测造影剂诱发的肾病(CIN)和 ACS 患者的一年期主要心脏不良事件(MACE)。对 1304 名 ACS 患者的冠状动脉造影记录进行了回顾性研究。评估了 SYNTAX 评分(SS)、SSII-经皮冠状动脉介入治疗(SSII-PCI)、SSII-冠状动脉旁路移植术(SSII-CABG)评分对 CIN 和 MACE 的预测价值。CIN和MACE比率的组合构成主要的复合终点。将 SSII-PCI 评分大于 32.55 的患者与评分较低的患者进行比较。三种评分系统都能预测主要复合终点[SS:曲线下面积(AUC):.718,P < .001(95% CI:.689-.747);SSII-PCI:AUC:.824,P < .001(95% CI:.800-.849);SSII-CABG:AUC:.778,P < .001(95% CI:.751-.805)]。接受者操作特征曲线的AUC比较显示,SSII-PCI评分比SS和SSII-CABG评分具有更好的预测价值。在多变量分析中,SSII-PCI 评分是主要复合终点的唯一预测因子(几率比:1.126,95% CI:1.107-1.146,P <0.001)。SSII-PCI 评分是预测休克、CABG、心肌梗死、支架血栓、CIN 发展和一年死亡率的重要工具。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of Predictive Value of SYNTAX-II Score for Adverse Cardiac Events and Clinical Outcomes in Patients With Acute Coronary Syndrome.

Prognostic information is important for the management of acute coronary syndrome (ACS). Our aim was to evaluate Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) score-II (SSII) for predicting contrast induced nephropathy (CIN) and one-year major adverse cardiac events (MACE) in ACS patients. Coronary angiographic recordings of 1304 ACS patients were retrospectively examined. Predictive values of SYNTAX score (SS), SSII-percutaneous coronary intervention (SSII-PCI), SSII-coronary artery bypass graft (SSII-CABG) scores for CIN and MACE were assessed. Combination of CIN and MACE ratios constituted primary composite end-point. Patients with SSII-PCI scores >32.55 were compared with patients with lower scores. All of the three scoring systems predicted the composite primary end-point [SS: Area under the curve (AUC): .718, P < .001 (95% CI: .689-.747), SSII-PCI: AUC: .824, P < .001 (95% CI: .800-.849), SSII-CABG: AUC: .778, P < .001 (95% CI: .751-.805)]. Comparison of AUC of receiver operating characteristic curves showed that SSII-PCI score had better predictive value than that of SS and SSII-CABG scores. In multivariate analysis, the only predictor of the primary composite end-point was SSII-PCI score (odds ratio: 1.126, 95% CI: 1.107-1.146, P < .001). SSII-PCI score was a valuable tool for prediction of shock, CABG, myocardial infarction, stent thrombosis, development of CIN and one-year mortality.

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来源期刊
Angiology
Angiology 医学-外周血管病
CiteScore
5.50
自引率
14.30%
发文量
180
审稿时长
6-12 weeks
期刊介绍: A presentation of original, peer-reviewed original articles, review and case reports relative to all phases of all vascular diseases, Angiology (ANG) offers more than a typical cardiology journal. With approximately 1000 pages per year covering diagnostic methods, therapeutic approaches, and clinical and laboratory research, ANG is among the most informative publications in the field of peripheral vascular and cardiovascular diseases. This journal is a member of the Committee on Publication Ethics (COPE). Average time from submission to first decision: 13 days
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