白细胞清除术中基线低钙血症和症状性低钙血症的发生率

IF 1.4 4区医学 Q4 HEMATOLOGY

Journal of Clinical Apheresis Pub Date : 2023-07-31 DOI:10.1002/jca.22076

Kimberly Bray BSN, RN, QIA, Carolyn Lynde RN, Trizzie Vu RN, Amy Patterson MSN, APRN, AOCNS, BMTCN, Richard R. Reich PhD, Tina M. Mason PhD, APRN, AOCN, AOCNS, FCNS, Hien D. Liu MD

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引用次数: 0

摘要

在接受白细胞摘除术的患者中，高达50%的患者报告有低钙症状。在预防或治疗低钙血症症状时，补钙没有固定的实践标准。这项描述性、回顾性研究的目的是确定基线低钙血症和症状性低钙血症在用柠檬酸葡萄糖溶液A进行白细胞采血期间的患病率，并确定与症状性低钙血症相关的患者特征。3%的患者在采血前发现有低钙血症，35%的患者在采血期间出现低钙血症症状。年龄较大、白蛋白水平较高和手术时间较长与低钙症状的风险增加有关。

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Prevalence of baseline hypocalcemia and symptomatic hypocalcemia during leukapheresis

Symptoms of hypocalcemia are reported in up to 50% of patients undergoing leukapheresis procedures. There is no set standard of practice for administering calcium supplementation in the prevention or treatment of hypocalcemia symptoms. The goal of this descriptive, retrospective study was to determine the prevalence of baseline hypocalcemia and symptomatic hypocalcemia during leukapheresis with acid citrate dextrose solution A and to identify patient characteristics associated with symptomatic hypocalcemia. Three percent of patients were found to have hypocalcemia before leukapheresis with 35% experiencing hypocalcemia symptoms during leukapheresis. Older age, higher albumin levels, and longer procedure time were associated with increased risk of hypocalcemia symptoms.

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来源期刊

Journal of Clinical Apheresis 医学-血液学

CiteScore

2.80

自引率

13.30%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Clinical Apheresis publishes articles dealing with all aspects of hemapheresis. Articles welcomed for review include those reporting basic research and clinical applications of therapeutic plasma exchange, therapeutic cytapheresis, therapeutic absorption, blood component collection and transfusion, donor recruitment and safety, administration of hemapheresis centers, and innovative applications of hemapheresis technology. Experimental studies, clinical trials, case reports, and concise reviews will be welcomed.