饮食与多囊肾病：营养、食物、饮食模式和实践意义

IF 2.8 3区医学 Q2 UROLOGY & NEPHROLOGY

Seminars in nephrology Pub Date : 2023-03-01 DOI:10.1016/j.semnephrol.2023.151405

Kelly Lambert PhD, RD, Adv APD , Robert Gardos BSc (Appl) , Helen Coolican BA, Dip Ed MA , Lauren Pickel BSc (Biol) , Hoon-Ki Sung PhD , Angela Yee-Moon Wang MD, PhD , Albert CM Ong DM, MA, FRCP

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引用次数: 1

摘要

多囊肾病（PKD）是一种慢性、进行性遗传性疾病，其特征是肾脏和其他器官中囊肿的异常发育和生长。人们越来越感兴趣地探索饮食调整是否可以预防或减缓PKD患者的病程。尽管加压素受体激动剂已成为推进PKD患者护理的一种新型药物治疗方法，但最近的几项具有里程碑意义的试验和临床发现也为潜在的饮食相关治疗策略提供了新的见解。在这篇综述中，我们总结了目前与营养、食物、饮食模式、囊肿生长和PKD进展有关的证据。我们还描述了PKD患者现有的循证饮食护理，并概述了推进循证饮食干预的潜在意义。Semin Nephrol 43:x-xx©2023 Elsevier股份有限公司保留所有权利。

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Diet and Polycystic Kidney Disease: Nutrients, Foods, Dietary Patterns, and Implications for Practice

Polycystic kidney disease (PKD) is a chronic, progressive hereditary condition characterized by abnormal development and growth of cysts in the kidneys and other organs. There is increasing interest in exploring whether dietary modifications may prevent or slow the disease course in people with PKD. Although vasopressin-receptor agonists have emerged as a novel drug treatment in advancing care for people with PKD, several recent landmark trials and clinical discoveries also have provided new insights into potential dietary-related therapeutic strategies. In this review, we summarize the current evidence pertaining to nutrients, foods, dietary patterns, cyst growth, and progression of PKD. We also describe existing evidence-based dietary care for people with PKD and outline the potential implications for advancing evidence-based dietary interventions.

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来源期刊

Seminars in nephrology 医学-泌尿学与肾脏学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Seminars in Nephrology is a timely source for the publication of new concepts and research findings relevant to the clinical practice of nephrology. Each issue is an organized compendium of practical information that serves as a lasting reference for nephrologists, internists and physicians in training.