{"title":"n -甲基- d -天冬氨酸受体脑炎的对症治疗。","authors":"Soon-Tae Lee","doi":"10.47936/encephalitis.2020.00045","DOIUrl":null,"url":null,"abstract":"<p><p><i>N</i>-methyl-D-aspartate receptor (NMDAR) encephalitis presents with multiple symptoms including memory loss, seizure, psychosis, aphasia, altered mentality, dyskinesia, autonomic dysfunction, and central hypoventilation. While immunotherapy protocols are improving, morbidity and mortality in the disease largely depend on supportive care to control intractable symptoms. However, no prospective or controlled trials have been conducted on immunotherapy or supportive care principles in the disease. Thus, this study discusses and shares experience and ideas for symptomatic care of NMDAR encephalitis.</p>","PeriodicalId":72904,"journal":{"name":"Encephalitis (Seoul, Korea)","volume":"1 1","pages":"4-6"},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/6c/encephalitis-2020-00045.PMC10295877.pdf","citationCount":"4","resultStr":"{\"title\":\"Symptomatic treatments of <i>N</i>-methyl-D-aspartate receptor encephalitis.\",\"authors\":\"Soon-Tae Lee\",\"doi\":\"10.47936/encephalitis.2020.00045\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><i>N</i>-methyl-D-aspartate receptor (NMDAR) encephalitis presents with multiple symptoms including memory loss, seizure, psychosis, aphasia, altered mentality, dyskinesia, autonomic dysfunction, and central hypoventilation. While immunotherapy protocols are improving, morbidity and mortality in the disease largely depend on supportive care to control intractable symptoms. However, no prospective or controlled trials have been conducted on immunotherapy or supportive care principles in the disease. Thus, this study discusses and shares experience and ideas for symptomatic care of NMDAR encephalitis.</p>\",\"PeriodicalId\":72904,\"journal\":{\"name\":\"Encephalitis (Seoul, Korea)\",\"volume\":\"1 1\",\"pages\":\"4-6\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/55/6c/encephalitis-2020-00045.PMC10295877.pdf\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Encephalitis (Seoul, Korea)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.47936/encephalitis.2020.00045\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Encephalitis (Seoul, Korea)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.47936/encephalitis.2020.00045","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 4
摘要
n -甲基- d -天冬氨酸受体(NMDAR)脑炎表现为多种症状,包括记忆丧失、癫痫发作、精神错乱、失语、思维改变、运动障碍、自主神经功能障碍和中心性低通气。虽然免疫治疗方案正在改进,但该病的发病率和死亡率在很大程度上取决于支持性护理来控制难治性症状。然而,没有前瞻性或对照试验进行免疫治疗或支持护理原则的疾病。因此,本研究对NMDAR脑炎的对症护理进行探讨和分享经验和思路。
Symptomatic treatments of N-methyl-D-aspartate receptor encephalitis.
N-methyl-D-aspartate receptor (NMDAR) encephalitis presents with multiple symptoms including memory loss, seizure, psychosis, aphasia, altered mentality, dyskinesia, autonomic dysfunction, and central hypoventilation. While immunotherapy protocols are improving, morbidity and mortality in the disease largely depend on supportive care to control intractable symptoms. However, no prospective or controlled trials have been conducted on immunotherapy or supportive care principles in the disease. Thus, this study discusses and shares experience and ideas for symptomatic care of NMDAR encephalitis.