前交叉韧带重建后脓毒性膝关节炎的治疗方法。

IF 2.9 2区 医学 Q1 ORTHOPEDICS
Oladimeji Ranti Babalola, Adebukola Adedoyin Babalola, Kehinde Adesola Alatishe
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引用次数: 0

摘要

回顾目的:前交叉韧带重建后的脓毒性膝关节炎是一种罕见但潜在有害的并发症。近年来,治疗这种潜在的破坏性并发症的主要方法包括在手术中采用广谱抗生素溶液预浸泡移植物,更积极地尝试防止移植物污染,并对确定的膝关节败血症病例进行早期和充分的治疗,无论移植物是否保留。然而,对于外科医生来说,在某些情况下,早期和适当的初始治疗可能是一个具有挑战性的决定。最近的研究发现:移植物预先浸泡在万古霉素中可以显著降低前交叉韧带重建后脓毒性膝关节炎的发生率。其他研究也记录了用庆大霉素预浸泡移植物的类似满意结果。在确定的感染病例中,在精心挑选的患者中,无论是保留移植物还是切除移植物并延迟重建前交叉韧带,冲洗和清创都能获得满意的结果。通过仔细选择患者,使用预防性抗生素,术中严格无菌,并在抗生素溶液中预先浸泡移植物,可以预防前交叉韧带重建后的脓毒性膝关节炎。移植物预浸泡的抗生素溶液的选择受外科医生的偏好、组织外显率、对移植物抗拉强度的影响、微生物的局部生物特征和敏感性模式的影响。确定病例的治疗方案取决于感染的阶段、移植物的状态和骨受累的程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Approaches to Septic Arthritis of the Knee Post Anterior Cruciate Ligament Reconstruction.

Purpose of review: Septic arthritis of the knee following anterior cruciate ligament reconstruction is a rare but potentially deleterious complication. The main approach to the management of this potentially devastating complication in recent years has involved a more aggressive attempt at preventing graft contamination during surgery with the adoption of the pre-soaking of the graft in broad-spectrum antibiotic solution, and early and adequate treatment of established cases of knee sepsis, with or without retention of the graft. However, what constitutes an early and adequate initial treatment may be a challenging decision for the surgeon to make in certain instances.

Recent findings: Graft pre-soaking in vancomycin has been noted to significantly reduce the incidence of septic arthritis of the knee following anterior cruciate ligament reconstruction. Other studies have recorded similar satisfactory results with graft pre-soaking in gentamycin. In established cases of infection, irrigation and debridement with either graft retention or graft excision with delayed re-construction of the anterior cruciate ligament have both given satisfactory results in well-selected patients. Septic arthritis of the knee following anterior cruciate ligament reconstruction can be prevented by careful patient selection, use of prophylactic antibiotics, strict asepsis during surgery, and graft pre-soaking in antibiotic solution. The choice of antibiotic solution for graft pre-soaking is influenced by the surgeon's preference, tissue penetrance, effect on graft tensile strength, local bio-gram of the micro-organisms, and the sensitivity pattern. The treatment option in established cases would depend on the stage of infection, state of the graft, and the extent of bony involvement.

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来源期刊
CiteScore
7.50
自引率
2.40%
发文量
64
期刊介绍: This journal intends to review the most significant recent developments in the field of musculoskeletal medicine. By providing clear, insightful, balanced contributions by expert world-renowned authors, the journal aims to serve all those involved in the diagnosis, treatment, management, and prevention of musculoskeletal-related conditions. We accomplish this aim by appointing authorities to serve as Section Editors in key subject areas, such as rehabilitation of the knee and hip, sports medicine, trauma, pediatrics, health policy, customization in arthroplasty, and rheumatology. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an Editorial Board of more than 20 diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research.
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