{"title":"超声和微泡结合用于药物传递,检测生物标志物。","authors":"Leslie Mertz","doi":"10.1109/MPULS.2023.3269759","DOIUrl":null,"url":null,"abstract":"<p><p>Microbubbles and ultrasound are no longer teaming up only as a way to enhance images. New technologies are now using the two to create physical pathways into cells for easier drug delivery, even into the cells of highly drug-resistant cancerous tumors and across the blood-brain barrier. Going further, a Texas research group has developed drug-carrying microbubbles that can complete targeted delivery themselves, and another group in Missouri has shown that two-way traffic in channels across the blood-brain barrier also allow biomarkers to flow out, which provides a new window into the brain as well as brain diseases.</p>","PeriodicalId":49065,"journal":{"name":"IEEE Pulse","volume":null,"pages":null},"PeriodicalIF":0.3000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ultrasound and Microbubbles Combine for Drug Delivery, Detecting Biomarkers.\",\"authors\":\"Leslie Mertz\",\"doi\":\"10.1109/MPULS.2023.3269759\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Microbubbles and ultrasound are no longer teaming up only as a way to enhance images. New technologies are now using the two to create physical pathways into cells for easier drug delivery, even into the cells of highly drug-resistant cancerous tumors and across the blood-brain barrier. Going further, a Texas research group has developed drug-carrying microbubbles that can complete targeted delivery themselves, and another group in Missouri has shown that two-way traffic in channels across the blood-brain barrier also allow biomarkers to flow out, which provides a new window into the brain as well as brain diseases.</p>\",\"PeriodicalId\":49065,\"journal\":{\"name\":\"IEEE Pulse\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.3000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Pulse\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.1109/MPULS.2023.3269759\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Pulse","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1109/MPULS.2023.3269759","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Ultrasound and Microbubbles Combine for Drug Delivery, Detecting Biomarkers.
Microbubbles and ultrasound are no longer teaming up only as a way to enhance images. New technologies are now using the two to create physical pathways into cells for easier drug delivery, even into the cells of highly drug-resistant cancerous tumors and across the blood-brain barrier. Going further, a Texas research group has developed drug-carrying microbubbles that can complete targeted delivery themselves, and another group in Missouri has shown that two-way traffic in channels across the blood-brain barrier also allow biomarkers to flow out, which provides a new window into the brain as well as brain diseases.
期刊介绍:
IEEE Pulse covers both general and technical articles on current technologies and methods used in biomedical and clinical engineering; societal implications of medical technologies; current news items; book reviews; patent descriptions; and correspondence. Special interest departments, students, law, clinical engineering, ethics, new products, society news, historical features and government.