Sarena Hayer, Ava D Mandelbaum, Lester Watch, Kimberly S Ryan, Madeline A Hedges, Jennifer A Manuzak, Charles A Easley, Danny J Schust, Jamie O Lo
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引用次数: 0
摘要
重要性：产前使用大麻的人数不断增加，这是一个重大的公共卫生问题。孕期和哺乳期吸食大麻与母婴发病率和死亡率增加有关：本综述旨在总结现有文献以及关于孕期或哺乳期使用大麻的现行建议：使用以下术语对 PubMed、Cochrane 图书馆和 Google Scholar 进行文献检索，以收集相关数据："大麻"、"大麻素"、"δ-9-四氢大麻酚"、"四氢大麻酚"、"大麻二酚"、"胎儿结局"、"围产期结局"、"妊娠 "和 "哺乳期"：对有关孕期和哺乳期吸食大麻的现有研究进行了回顾，结果表明，吸食大麻与早产、入住新生儿重症监护室、低出生体重和小于胎龄婴儿的风险增加有关：亟需对孕期和哺乳期吸食大麻的影响进行研究。这是进一步开展患者教育、制定干预措施和有针对性地进行产前监测以减轻对孕产妇和胎儿健康的不利影响之前必须迈出的第一步。
Importance: Prenatal cannabis use is rising and is a major public health issue. Cannabis use in pregnancy and during lactation has been associated with increased maternal and offspring morbidity and mortality.
Objective: This review aims to summarize the existing literature and current recommendations for cannabis use during pregnancy or lactation.
Evidence acquisition: A PubMed, Cochrane Library, and Google Scholar literature search using the following terms was performed to gather relevant data: "cannabis," "cannabinoid," "delta-9-tetrahydrocannabinol," "THC," "cannabidiol," "fetal outcomes," "perinatal outcomes," "pregnancy," and "lactation."
Results: Available studies on cannabis use in pregnancy and during lactation were reviewed and support an association with increased risk of preterm birth, neonatal intensive care unit admission, low birth weight, and small-for-gestational-age infants.
Conclusion and relevance: There is a critical need for research on the effects of cannabis use in pregnancy and during lactation. This is a necessary first step before furthering patient education, developing interventions, and targeting antenatal surveillance to ameliorate the adverse impacts on maternal and fetal health.
期刊介绍：
Each monthly issue of Obstetrical & Gynecological Survey presents summaries of the most timely and clinically relevant research being published worldwide. These concise, easy-to-read summaries provide expert insight into how to apply the latest research to patient care. The accompanying editorial commentary puts the studies into perspective and supplies authoritative guidance. The result is a valuable, time-saving resource for busy clinicians.
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