减肥手术前后肠易激综合征样症状与短链可发酵碳水化合物消耗的关系:一项观察性前瞻性研究

IF 1.3 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY
P Van Ouytsel, H Piessevaux, A Szalai, P Loi, H Louis
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引用次数: 1

摘要

背景和目的:肠易激综合征(IBS)样症状在减肥手术后很常见。本研究旨在评估减肥手术前后IBS症状严重程度的频率及其与短链可发酵碳水化合物(FODMAPs)摄入的关系。患者和方法:通过经验证的问卷和工具(肠易激综合征严重程度评分系统(IBS SSS)、布里斯托尔大便量表(BSS)、短期生活质量12(SF-12)、医院焦虑和抑郁量表(HAD)),在减肥手术前、手术后6个月和12个月前瞻性评估肥胖患者队列中的IBS症状严重程度。FODMAPs的摄入及其与IBS症状严重程度的关系通过使用关注高FODMAPs食物摄入的食物频率问卷进行评估。结果:51名患者(41名女性;平均年龄41岁(SD:12)),84%接受袖状胃切除术,16%接受Roux-en-Y胃旁路术。43%的患者在手术前、58%的患者在6个月时和33%的患者在12个月时观察到与IBS兼容的症状(NS,p值分别为0197和0414)。在一个多变量模型中,发现IBS SSS评分与6个月时的乳糖消耗量(β=+58,1;p=0.03)和12个月时多元醇消耗量(α=+112,6;p=0.01)之间存在显著相关性。结论:肥胖患者在减肥手术前经常出现轻度至中度IBS症状。减肥手术后观察到乳糖和多元醇的摄入与IBS SSS评分之间存在显著关联,这表明IBS症状的严重程度与某些特定FODMAP的摄入之间存在潜在联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Irritable bowel syndrome-like symptoms before and after bariatric surgery and association with short-chain fermentable carbohydrates consumption: an observational prospective study.
Background and aims Irritable Bowel Syndrome (IBS)-like symptoms are frequent following bariatric surgery. This study aims to evaluate the frequency of IBS symptoms severity before and after bariatric surgery and their association with short-chain fermentable carbohydrates (FODMAPs) consumption. Patients and methods IBS symptoms severity in a cohort of obese patients was evaluated prospectively before, 6 and 12 months after bariatric surgery by validated questionnaires and tools (Irritable Bowel Syndrome Severity Scoring System (IBS SSS), Bristol Stool Scale (BSS), Quality of Life Short- Form-12 (SF-12), Hospital Anxiety and Depression scale (HAD)). FODMAPs consumption and its association with IBS symptom severity was evaluated by using a food frequency questionnaire focused on high-FODMAPs food consumption. Results Fifty-one patients were included (41 female; mean age 41 years (SD: 12)), 84% received a sleeve gastrectomy, and 16% a Roux-en-Y gastric bypass. Symptoms compatible with IBS were observed in 43% of patients before surgery, in 58% of patients at 6 months and 33% at 12 months (NS, p-value=0,197 and 0,414). In a multivariate model, a significant association was found between the IBS SSS score and lactose consumption at 6 months (β = + 58, 1; p = 0.03), and with polyols consumption at 12 months (β = + 112,6; p = 0.01). Conclusions Mild to moderate IBS symptoms are frequent in obese patients before bariatric surgery. A significant association between lactose and polyols consumption and IBS SSS score was observed after bariatric surgery, suggesting a potential link between the severity of IBS symptoms and some specific FODMAPs consumption.
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来源期刊
Acta gastro-enterologica Belgica
Acta gastro-enterologica Belgica Medicine-Gastroenterology
CiteScore
2.30
自引率
20.00%
发文量
78
期刊介绍: The Journal Acta Gastro-Enterologica Belgica principally publishes peer-reviewed original manuscripts, reviews, letters to editors, book reviews and guidelines in the field of clinical Gastroenterology and Hepatology, including digestive oncology, digestive pathology, as well as nutrition. Pure animal or in vitro work will not be considered for publication in the Journal. Translational research papers (including sections of animal or in vitro work) are considered by the Journal if they have a clear relationship to or relevance for clinical hepato-gastroenterology (screening, disease mechanisms and/or new therapies). Case reports and clinical images will be accepted if they represent an important contribution to the description, the pathogenesis or the treatment of a specific gastroenterology or liver problem. The language of the Journal is English. Papers from any country will be considered for publication. Manuscripts submitted to the Journal should not have been published previously (in English or any other language), nor should they be under consideration for publication elsewhere. Unsolicited papers are peer-reviewed before it is decided whether they should be accepted, rejected, or returned for revision. Manuscripts that do not meet the presentation criteria (as indicated below) will be returned to the authors. Papers that go too far beyond the scope of the journal will be also returned to the authors by the editorial board generally within 2 weeks. The Journal reserves the right to edit the language of papers accepted for publication for clarity and correctness, and to make formal changes to ensure compliance with AGEB’s style. Authors have the opportunity to review such changes in the proofs.
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