{"title":"超短客观警觉性评估:3分钟PVT(PVT-BA)的自适应持续时间版本准确跟踪睡眠限制引起的心理运动警惕性的变化。","authors":"Mathias Basner","doi":"10.1093/sleepadvances/zpac038","DOIUrl":null,"url":null,"abstract":"<p><strong>Study objectives: </strong>The Psychomotor Vigilance Test (PVT) is a widely used and sensitive assay of the cognitive deficits associated with sleep loss and circadian misalignment. As even shorter versions of the PVT are often considered too long, I developed and validated an adaptive duration version of the 3 min PVT (PVT-BA).</p><p><strong>Methods: </strong>The PVT-BA algorithm was trained on data from 31 subjects participating in a total sleep deprivation protocol and validated in 43 subjects undergoing 5 days of partial sleep restriction under controlled laboratory conditions. With each subject response, the algorithm updated the odds of the test being high, medium or low performance based on lapses plus false starts on the full 3 min PVT-B.</p><p><strong>Results: </strong>With a decision threshold of 99.619%, PVT-BA classified 95.1% of training data tests correctly without incorrect classifications across two performance categories (i.e. high as low or low as high) and resulted in an average test duration of 1 min 43 s with a minimum duration of 16.4 s. Agreement corrected for chance between PVT-B and PVT-BA was \"almost perfect\" for both the training (kappa = 0.92) and validation data (kappa = 0.85). Across the three performance categories and data sets, sensitivity averaged 92.2% (range 74.9-100%) and specificity averaged 96.0% (range 88.3-99.2%).</p><p><strong>Conclusions: </strong>PVT-BA is an accurate adaptive version of PVT-B and, to my knowledge, the shortest version to date that maintains key properties of the standard 10 min duration PVT. PVT-BA will facilitate the use of the PVT in settings in which it was previously considered impractical.</p>","PeriodicalId":74808,"journal":{"name":"Sleep advances : a journal of the Sleep Research Society","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/3f/zpac038.PMC10104405.pdf","citationCount":"2","resultStr":"{\"title\":\"Ultra-short objective alertness assessment: an adaptive duration version of the 3 minute PVT (PVT-BA) accurately tracks changes in psychomotor vigilance induced by sleep restriction.\",\"authors\":\"Mathias Basner\",\"doi\":\"10.1093/sleepadvances/zpac038\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study objectives: </strong>The Psychomotor Vigilance Test (PVT) is a widely used and sensitive assay of the cognitive deficits associated with sleep loss and circadian misalignment. As even shorter versions of the PVT are often considered too long, I developed and validated an adaptive duration version of the 3 min PVT (PVT-BA).</p><p><strong>Methods: </strong>The PVT-BA algorithm was trained on data from 31 subjects participating in a total sleep deprivation protocol and validated in 43 subjects undergoing 5 days of partial sleep restriction under controlled laboratory conditions. With each subject response, the algorithm updated the odds of the test being high, medium or low performance based on lapses plus false starts on the full 3 min PVT-B.</p><p><strong>Results: </strong>With a decision threshold of 99.619%, PVT-BA classified 95.1% of training data tests correctly without incorrect classifications across two performance categories (i.e. high as low or low as high) and resulted in an average test duration of 1 min 43 s with a minimum duration of 16.4 s. Agreement corrected for chance between PVT-B and PVT-BA was \\\"almost perfect\\\" for both the training (kappa = 0.92) and validation data (kappa = 0.85). Across the three performance categories and data sets, sensitivity averaged 92.2% (range 74.9-100%) and specificity averaged 96.0% (range 88.3-99.2%).</p><p><strong>Conclusions: </strong>PVT-BA is an accurate adaptive version of PVT-B and, to my knowledge, the shortest version to date that maintains key properties of the standard 10 min duration PVT. PVT-BA will facilitate the use of the PVT in settings in which it was previously considered impractical.</p>\",\"PeriodicalId\":74808,\"journal\":{\"name\":\"Sleep advances : a journal of the Sleep Research Society\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9f/3f/zpac038.PMC10104405.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Sleep advances : a journal of the Sleep Research Society\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/sleepadvances/zpac038\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Sleep advances : a journal of the Sleep Research Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/sleepadvances/zpac038","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
Ultra-short objective alertness assessment: an adaptive duration version of the 3 minute PVT (PVT-BA) accurately tracks changes in psychomotor vigilance induced by sleep restriction.
Study objectives: The Psychomotor Vigilance Test (PVT) is a widely used and sensitive assay of the cognitive deficits associated with sleep loss and circadian misalignment. As even shorter versions of the PVT are often considered too long, I developed and validated an adaptive duration version of the 3 min PVT (PVT-BA).
Methods: The PVT-BA algorithm was trained on data from 31 subjects participating in a total sleep deprivation protocol and validated in 43 subjects undergoing 5 days of partial sleep restriction under controlled laboratory conditions. With each subject response, the algorithm updated the odds of the test being high, medium or low performance based on lapses plus false starts on the full 3 min PVT-B.
Results: With a decision threshold of 99.619%, PVT-BA classified 95.1% of training data tests correctly without incorrect classifications across two performance categories (i.e. high as low or low as high) and resulted in an average test duration of 1 min 43 s with a minimum duration of 16.4 s. Agreement corrected for chance between PVT-B and PVT-BA was "almost perfect" for both the training (kappa = 0.92) and validation data (kappa = 0.85). Across the three performance categories and data sets, sensitivity averaged 92.2% (range 74.9-100%) and specificity averaged 96.0% (range 88.3-99.2%).
Conclusions: PVT-BA is an accurate adaptive version of PVT-B and, to my knowledge, the shortest version to date that maintains key properties of the standard 10 min duration PVT. PVT-BA will facilitate the use of the PVT in settings in which it was previously considered impractical.