中期正电子发射断层成像在头颈部鳞状细胞癌适应性放射治疗中的应用。

IF 2.6 4区医学 Q3 ONCOLOGY

Cancer journal Pub Date : 2023-07-01 DOI:10.1097/PPO.0000000000000669

Benjamin S Rosen, Neil Vaishampayan, Yue Cao, Michelle L Mierzwa

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引用次数: 0

摘要

摘要：在这篇文章中，作为早期反应生物标志物特刊的一部分，我们回顾了目前支持在放化疗期间使用正电子发射断层扫描（PET）成像来为头颈部鳞状细胞癌的生物适应性放射治疗提供信息的证据。我们回顾了近30年来涵盖这一主题的文献，包括各种放射性示踪剂的使用和新的预测PET生物标志物的发现。通过了解观察性试验如何为当前的介入性临床试验提供信息，我们希望这篇综述将鼓励研究人员和临床医生在新的试验设计中纳入PET反应标准，以推进生物优化放射治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The Utility of Interim Positron Emission Tomography Imaging to Inform Adaptive Radiotherapy for Head and Neck Squamous Cell Carcinoma.

Abstract: In this article, as part of this special issue on biomarkers of early response, we review the current evidence to support the use of positron emission tomography (PET) imaging during chemoradiation therapy to inform biologically adaptive radiotherapy for head and neck squamous cell carcinoma. We review literature covering this topic spanning nearly 3 decades, including the use of various radiotracers and discoveries of novel predictive PET biomarkers. Through understanding how observational trials have informed current interventional clinical trials, we hope that this review will encourage researchers and clinicians to incorporate PET response criteria in new trial designs to advance biologically optimized radiotherapy.

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来源期刊

Cancer journal 医学-肿瘤学

CiteScore

3.90

自引率

0.00%

发文量

102

审稿时长

7.5 months

期刊介绍： The Cancer Journal: The Journal of Principles & Practice of Oncology provides an integrated view of modern oncology across all disciplines. The Journal publishes original research and reviews, and keeps readers current on content published in the book Cancer: Principles & Practice of Oncology.