拉沙病毒的生态学。

3区医学 Q2 Medicine

Current topics in microbiology and immunology Pub Date : 2023-01-01 DOI:10.1007/82_2020_231

Allison R Smither, Antoinette R Bell-Kareem

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引用次数: 7

摘要

生活在拉沙热流行热点地区的人，会通过主要宿主储库 Mastomys natalensis 的外溢而反复接触拉沙病毒（LASV）。尽管M. natalensis广泛分布于撒哈拉以南非洲地区，但拉沙热却只出现在西非。近年来，又发现了新的拉沙热病毒储库。对啮齿动物的栖息地、繁殖和生殖能力、运动模式和空间偏好的研究对于制定拉沙热预防措施至关重要。对进化的深入了解也增加了我们对密切相关的哺乳动物病毒在整个非洲大陆啮齿动物中分布情况的了解。

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Ecology of Lassa Virus.

Individuals living in endemic hotspots of Lassa fever have recurrent exposure to Lassa virus (LASV) via spillover from the primary host reservoir Mastomys natalensis. Despite M. natalensis being broadly distributed across sub-Saharan Africa, Lassa fever is only found in West Africa. In recent years, new LASV reservoirs have been identified. Erudition of rodent habitats, reproduction and fecundity, movement patterns, and spatial preferences are essential to institute preventative measures against Lassa fever. Evolutionary insights have also added to our knowledge of closely related mammarenavirus distribution amongst rodents throughout the continent.

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来源期刊

Current topics in microbiology and immunology 医学-免疫学

CiteScore

5.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The review series Current Topics in Microbiology and Immunology provides a synthesis of the latest research findings in the areas of molecular immunology, bacteriology and virology. Each timely volume contains a wealth of information on the featured subject. This review series is designed to provide access to up-to-date, often previously unpublished information.