在大流行病时代平等地进行基因组监测的重要性。

IF 1.8 4区 生物学 Q3 BIOLOGY
Biologia futura Pub Date : 2023-06-01 Epub Date: 2023-05-18 DOI:10.1007/s42977-023-00164-5
Safia Zeghbib, Gábor Kemenesi, Ferenc Jakab
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引用次数: 0

摘要

目前,基因组流行病学已成为调查疾病爆发期间的传播情况以及未来应对新出现的人畜共患病的准备工作的核心组成部分。在过去几十年中,出现了几种病毒性疾病,强调了分子流行病学在追踪传播途径、支持适当的缓解措施和开发适当疫苗方面的重要性。在这篇透视文章中,我们总结了迄今为止在基因组流行病学领域所做的工作以及未来应考虑的问题。我们追溯了长期以来应对人畜共患病的方法和方案。无论是小规模疫情,如 2002 年在中国广东首次发现的严重急性呼吸系统综合征(SARS)疫情,还是全球性大流行,如 2019 年以来我们正在经历的大流行,当时严重急性呼吸系统综合征 2(SARS-CoV-2)病毒在中国武汉继几例肺炎病例之后出现,随后在全球范围内传播。我们探讨了依靠基因组流行病学所带来的益处和遇到的不足,并明确提出了世界各地,尤其是经济欠发达国家在获取这些工具方面存在的不公平弊端。为了有效应对未来的流行病,在全球范围内努力实现更好的测序公平至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The importance of equally accessible genomic surveillance in the age of pandemics.

The importance of equally accessible genomic surveillance in the age of pandemics.

Genomic epidemiology is now a core component in investigating the spread of a disease during an outbreak and for future preparedness to tackle emerging zoonoses. During the last decades, several viral diseases arose and emphasized the importance of molecular epidemiology in tracking the dispersal route, supporting proper mitigation measures, and appropriate vaccine development. In this perspective article, we summarized what has been done so far in the genomic epidemiology field and what should be considered in the future. We traced back the methods and protocols employed over time for zoonotic disease response. Either to small outbreaks such as the severe acute respiratory syndrome (SARS) outbreak identified first in 2002 in Guangdong, China, or to a global pandemic like the one that we are experiencing now since 2019 when the severe acute respiratory syndrome 2 (SARS-CoV-2) virus emerged in Wuhan, China, following several pneumonia cases, and subsequently spread worldwide. We explored both the benefits and shortages encountered when relying on genomic epidemiology, and we clearly present the disadvantages of inequity in accessing these tools around the world, especially in countries with less developed economies. For effectively addressing future pandemics, it is crucial to work for better sequencing equity around the globe.

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来源期刊
Biologia futura
Biologia futura Agricultural and Biological Sciences-Agricultural and Biological Sciences (all)
CiteScore
3.50
自引率
0.00%
发文量
27
期刊介绍: How can the scientific knowledge we possess now influence that future? That is, the FUTURE of Earth and life − of humankind. Can we make choices in the present to change our future? How can 21st century biological research ask proper scientific questions and find solid answers? Addressing these questions is the main goal of Biologia Futura (formerly Acta Biologica Hungarica). In keeping with the name, the new mission is to focus on areas of biology where major advances are to be expected, areas of biology with strong inter-disciplinary connection and to provide new avenues for future research in biology. Biologia Futura aims to publish articles from all fields of biology.
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