{"title":"调查Nemazee教学医院新冠肺炎患者肺栓塞的患病率、预测因素和危险因素。","authors":"Mahnaz Yadollahi, Hessam Hosseinalipour, Muhammad Alinaqi, Mehrdad Karajizadeh, Mehrdad Jowkar, Kazem Jamali, Maryam Yadollahi, Pooria Fazeli","doi":"10.5045/br.2023.2023076","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Pulmonary thromboembolism (PTE) is a significant contributing factor to vascular diseases. This study aimed to determine the prevalence of pulmonary thromboembolism and its predisposing factors in patients with COVID-19.</p><p><strong>Methods: </strong>This cross-sectional study included 284 patients with COVID-19 who were admitted to Nemazee Teaching Hospital (Shiraz, Iran) between June and August 2021. All patients were diagnosed with COVID-19 by a physician based on clinical symptoms or positive polymerase chain reaction (PCR) test results. The collected data included demographic data and laboratory findings. Data were analyzed using the SPSS software. <i>P</i>≤0.05 was considered statistically significant.</p><p><strong>Results: </strong>There was a significant difference in the mean age between the PTE group and non-PTE group (<i>P</i>=0.037). Moreover, the PTE group had a significantly higher prevalence of hypertension (36.7% vs. 21.8%, <i>P</i>=0.019), myocardial infarction (4.5% vs. 0%, <i>P</i>=0.006), and stroke (23.9% vs. 4.9%, <i>P</i>=0.0001). Direct bilirubin (<i>P</i>=0.03) and albumin (<i>P</i>=0.04) levels significantly differed between the PTE and non-PTE groups. Notably, there was a significant difference in the partial thromboplastin time (<i>P</i>=0.04) between the PTE and non-PTE groups. A regression analysis indicated that age (OR, 1.02; 95% CI, 1.00‒1.004; <i>P</i>=0.005), blood pressure (OR, 2.07; 95% CI, 1.12‒3.85; <i>P</i>=0.02), heart attack (OR, 1.02; 95% CI, 1.28‒6.06; <i>P</i>=0.009), and albumin level (OR, 0.39; 95% CI, 0.16‒0.97; <i>P</i>=0.04) were all independent predictors of PTE development.</p><p><strong>Conclusion: </strong>Regression analysis revealed that age, blood pressure, heart attack, and albumin levels were independent predictors of PTE.</p>","PeriodicalId":46224,"journal":{"name":"Blood Research","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/f4/br-58-3-127.PMC10548293.pdf","citationCount":"0","resultStr":"{\"title\":\"Investigating the prevalence of and predictive and risk factors for pulmonary embolism in patients with COVID-19 in Nemazee Teaching Hospital.\",\"authors\":\"Mahnaz Yadollahi, Hessam Hosseinalipour, Muhammad Alinaqi, Mehrdad Karajizadeh, Mehrdad Jowkar, Kazem Jamali, Maryam Yadollahi, Pooria Fazeli\",\"doi\":\"10.5045/br.2023.2023076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Pulmonary thromboembolism (PTE) is a significant contributing factor to vascular diseases. This study aimed to determine the prevalence of pulmonary thromboembolism and its predisposing factors in patients with COVID-19.</p><p><strong>Methods: </strong>This cross-sectional study included 284 patients with COVID-19 who were admitted to Nemazee Teaching Hospital (Shiraz, Iran) between June and August 2021. All patients were diagnosed with COVID-19 by a physician based on clinical symptoms or positive polymerase chain reaction (PCR) test results. The collected data included demographic data and laboratory findings. Data were analyzed using the SPSS software. <i>P</i>≤0.05 was considered statistically significant.</p><p><strong>Results: </strong>There was a significant difference in the mean age between the PTE group and non-PTE group (<i>P</i>=0.037). Moreover, the PTE group had a significantly higher prevalence of hypertension (36.7% vs. 21.8%, <i>P</i>=0.019), myocardial infarction (4.5% vs. 0%, <i>P</i>=0.006), and stroke (23.9% vs. 4.9%, <i>P</i>=0.0001). Direct bilirubin (<i>P</i>=0.03) and albumin (<i>P</i>=0.04) levels significantly differed between the PTE and non-PTE groups. Notably, there was a significant difference in the partial thromboplastin time (<i>P</i>=0.04) between the PTE and non-PTE groups. A regression analysis indicated that age (OR, 1.02; 95% CI, 1.00‒1.004; <i>P</i>=0.005), blood pressure (OR, 2.07; 95% CI, 1.12‒3.85; <i>P</i>=0.02), heart attack (OR, 1.02; 95% CI, 1.28‒6.06; <i>P</i>=0.009), and albumin level (OR, 0.39; 95% CI, 0.16‒0.97; <i>P</i>=0.04) were all independent predictors of PTE development.</p><p><strong>Conclusion: </strong>Regression analysis revealed that age, blood pressure, heart attack, and albumin levels were independent predictors of PTE.</p>\",\"PeriodicalId\":46224,\"journal\":{\"name\":\"Blood Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2023-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/f4/br-58-3-127.PMC10548293.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Blood Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5045/br.2023.2023076\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/7/11 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"HEMATOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Blood Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5045/br.2023.2023076","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/7/11 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"HEMATOLOGY","Score":null,"Total":0}
Investigating the prevalence of and predictive and risk factors for pulmonary embolism in patients with COVID-19 in Nemazee Teaching Hospital.
Background: Pulmonary thromboembolism (PTE) is a significant contributing factor to vascular diseases. This study aimed to determine the prevalence of pulmonary thromboembolism and its predisposing factors in patients with COVID-19.
Methods: This cross-sectional study included 284 patients with COVID-19 who were admitted to Nemazee Teaching Hospital (Shiraz, Iran) between June and August 2021. All patients were diagnosed with COVID-19 by a physician based on clinical symptoms or positive polymerase chain reaction (PCR) test results. The collected data included demographic data and laboratory findings. Data were analyzed using the SPSS software. P≤0.05 was considered statistically significant.
Results: There was a significant difference in the mean age between the PTE group and non-PTE group (P=0.037). Moreover, the PTE group had a significantly higher prevalence of hypertension (36.7% vs. 21.8%, P=0.019), myocardial infarction (4.5% vs. 0%, P=0.006), and stroke (23.9% vs. 4.9%, P=0.0001). Direct bilirubin (P=0.03) and albumin (P=0.04) levels significantly differed between the PTE and non-PTE groups. Notably, there was a significant difference in the partial thromboplastin time (P=0.04) between the PTE and non-PTE groups. A regression analysis indicated that age (OR, 1.02; 95% CI, 1.00‒1.004; P=0.005), blood pressure (OR, 2.07; 95% CI, 1.12‒3.85; P=0.02), heart attack (OR, 1.02; 95% CI, 1.28‒6.06; P=0.009), and albumin level (OR, 0.39; 95% CI, 0.16‒0.97; P=0.04) were all independent predictors of PTE development.
Conclusion: Regression analysis revealed that age, blood pressure, heart attack, and albumin levels were independent predictors of PTE.
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