Henning Bahlburg, Tabea Hellmann, Karl Tully, Marius Cristian Butea-Bocu, Moritz Reike, Florian Roghmann, Joachim Noldus, Guido Müller
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Multivariate logistic regression was performed to identify predictors for high psychosocial distress.</p><p><strong>Results: </strong>Four-hundred and forty-seven patients (326 male, 121 female) received an IC, while 395 patients (357 male, 38 female) received an INB. Health-related QoL improved steadily in the whole cohort during follow-up. Patients with an INB reported better physical function but suffered more from diarrhea and financial worries. Patients with an IC reported reduced satisfaction with their body image, increased worries about the future, and suffered more from constipation. Psychosocial distress increased significantly during follow-up. One year after surgery, 43.1% of patients suffered from high psychosocial distress. Multivariate regression analysis identified age ≤ 59 years (OR 1.731; CI 1.056-2.838; p = 0.030) and lymph node metastases (OR 2.073; CI 1.133-3.793; p = 0.018) as independent predictors for high psychosocial distress.</p><p><strong>Conclusion: </strong>QoL improves significantly in all patients one year after RC. However, psychosocial distress remains high in a substantial number of patients.</p><p><strong>Implications for cancer survivors: </strong>To prevent chronic psychological disorders, easily accessible opportunities for psycho-oncological counseling are needed for patients following RC.</p>","PeriodicalId":15284,"journal":{"name":"Journal of Cancer Survivorship","volume":null,"pages":null},"PeriodicalIF":3.1000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424671/pdf/","citationCount":"0","resultStr":"{\"title\":\"Psychosocial distress and quality of life in patients after radical cystectomy - one year follow-up in 842 German patients.\",\"authors\":\"Henning Bahlburg, Tabea Hellmann, Karl Tully, Marius Cristian Butea-Bocu, Moritz Reike, Florian Roghmann, Joachim Noldus, Guido Müller\",\"doi\":\"10.1007/s11764-023-01400-6\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This study aims to report on psychosocial distress and QoL in bladder cancer patients after radical cystectomy (RC) and urinary diversion to obtain a better basis for patient counseling and postoperative care.</p><p><strong>Methods: </strong>The study relied on prospectively collected data for 842 patients, who underwent three weeks of inpatient rehabilitation after RC and creation of an ileal conduit (IC) or ileal neobladder (INB). 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引用次数: 0
摘要
目的:本研究旨在报告根治性膀胱切除术(RC)和尿路改道术后膀胱癌患者的社会心理压力和生活质量,为患者咨询和术后护理提供更好的依据:该研究依赖于前瞻性收集的 842 名患者的数据,这些患者在接受根治性膀胱切除术和建立回肠导尿管(IC)或回肠新膀胱(INB)后接受了为期三周的住院康复治疗。通过有效问卷收集了有关QoL和社会心理压力的数据。采用多变量逻辑回归法确定高社会心理压力的预测因素:447名患者(326名男性,121名女性)接受了IC治疗,395名患者(357名男性,38名女性)接受了INB治疗。在随访期间,整个组群的健康相关生活质量稳步提高。接受 INB 治疗的患者表示身体机能有所改善,但腹泻和经济问题更为严重。接受 IC 治疗的患者对自己身体形象的满意度降低,对未来的担忧增加,便秘症状加重。在随访期间,心理社会困扰明显增加。术后一年,43.1%的患者遭受了严重的心理社会困扰。多变量回归分析发现,年龄≤59岁(OR 1.731;CI 1.056-2.838;P = 0.030)和淋巴结转移(OR 2.073;CI 1.133-3.793;P = 0.018)是高社会心理压力的独立预测因素:结论:所有患者的 QoL 在 RC 一年后都有明显改善。结论:所有患者在 RC 一年后的 QoL 都有明显改善,但仍有相当多的患者面临严重的心理社会问题:对癌症幸存者的启示:为了预防慢性心理障碍,需要为 RC 患者提供方便的肿瘤心理咨询机会。
Psychosocial distress and quality of life in patients after radical cystectomy - one year follow-up in 842 German patients.
Purpose: This study aims to report on psychosocial distress and QoL in bladder cancer patients after radical cystectomy (RC) and urinary diversion to obtain a better basis for patient counseling and postoperative care.
Methods: The study relied on prospectively collected data for 842 patients, who underwent three weeks of inpatient rehabilitation after RC and creation of an ileal conduit (IC) or ileal neobladder (INB). Data on QoL and psychosocial distress were collected by validated questionnaires. Multivariate logistic regression was performed to identify predictors for high psychosocial distress.
Results: Four-hundred and forty-seven patients (326 male, 121 female) received an IC, while 395 patients (357 male, 38 female) received an INB. Health-related QoL improved steadily in the whole cohort during follow-up. Patients with an INB reported better physical function but suffered more from diarrhea and financial worries. Patients with an IC reported reduced satisfaction with their body image, increased worries about the future, and suffered more from constipation. Psychosocial distress increased significantly during follow-up. One year after surgery, 43.1% of patients suffered from high psychosocial distress. Multivariate regression analysis identified age ≤ 59 years (OR 1.731; CI 1.056-2.838; p = 0.030) and lymph node metastases (OR 2.073; CI 1.133-3.793; p = 0.018) as independent predictors for high psychosocial distress.
Conclusion: QoL improves significantly in all patients one year after RC. However, psychosocial distress remains high in a substantial number of patients.
Implications for cancer survivors: To prevent chronic psychological disorders, easily accessible opportunities for psycho-oncological counseling are needed for patients following RC.
期刊介绍:
Cancer survivorship is a worldwide concern. The aim of this multidisciplinary journal is to provide a global forum for new knowledge related to cancer survivorship. The journal publishes peer-reviewed papers relevant to improving the understanding, prevention, and management of the multiple areas related to cancer survivorship that can affect quality of care, access to care, longevity, and quality of life. It is a forum for research on humans (both laboratory and clinical), clinical studies, systematic and meta-analytic literature reviews, policy studies, and in rare situations case studies as long as they provide a new observation that should be followed up on to improve outcomes related to cancer survivors. Published articles represent a broad range of fields including oncology, primary care, physical medicine and rehabilitation, many other medical and nursing specialties, nursing, health services research, physical and occupational therapy, public health, behavioral medicine, psychology, social work, evidence-based policy, health economics, biobehavioral mechanisms, and qualitative analyses. The journal focuses exclusively on adult cancer survivors, young adult cancer survivors, and childhood cancer survivors who are young adults. Submissions must target those diagnosed with and treated for cancer.