马齿苋两种新天然产物及其生物活性研究。

IF 1.8 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences Pub Date : 2023-05-25 DOI:10.1515/znc-2022-0197

Mingyang Song, Zheming Ying, Xixiang Ying, Lianqun Jia, Guanlin Yang

引用次数: 0

摘要

从马蹄苋中分离到两个新的生物碱天然产物，鉴定为((2R,3S,4R,5R)-5-(2,4-二氧基-3,4-二氢嘧啶-1(2H)-基)-3,4-二羟基四氢呋喃-2-基)乙酸甲酯(1)和(5-羟基吡啶-2-基)乙酸甲酯(2)。采用一维、二维NMR和UHPLC-ESI-QTOF/MS等波谱方法鉴定了它们的结构。同时，两种化合物均具有抗炎和抗胆碱酯酶活性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Two new natural products from Portulaca oleracea L. and their bioactivities.

Two new natural products, belonging to alkaloids, identified as ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl acetate (1) and (5-hydroxypyridin-2-yl)methyl acetate (2), were isolated from Portulaca oleracea L. The structures were identified by spectroscopic methods, including 1D, 2D NMR, and UHPLC-ESI-QTOF/MS methods. Meanwhile, the anti-inflammatory and anticholinesterase bioactivities were found in these two compounds.

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来源期刊

Zeitschrift Fur Naturforschung Section C-A Journal of Biosciences 生物-生化与分子生物学

CiteScore

4.10

自引率

5.00%

发文量

期刊介绍： A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) is an international scientific journal and a community resource for the emerging field of natural and natural-like products. The journal publishes original research on the isolation (including structure elucidation), bio-chemical synthesis and bioactivities of natural products, their biochemistry, pharmacology, biotechnology, and their biological activity and innovative developed computational methods for predicting the structure and/or function of natural products. A Journal of Biosciences: Zeitschrift für Naturforschung C (ZNC) welcomes research papers in fields on the chemistry-biology boundary which address scientific ideas and approaches to generate and understand natural compounds on a molecular level and/or use them to stimulate and manipulate biological processes.