Sepideh Hatamikia , Gunpreet Oberoi , Anna Zacher , Gernot Kronreif , Wolfgang Birkfellner , Joachim Kettenbach , Stefanie Ponti , Andrea Lorenz , Martin Buschmann , Laszlo Jaksa , Nikolaus Irnstorfer , Ewald Unger
{"title":"利用Polyjet技术增材制造模拟CBCT软组织辐射衰减的测试模型","authors":"Sepideh Hatamikia , Gunpreet Oberoi , Anna Zacher , Gernot Kronreif , Wolfgang Birkfellner , Joachim Kettenbach , Stefanie Ponti , Andrea Lorenz , Martin Buschmann , Laszlo Jaksa , Nikolaus Irnstorfer , Ewald Unger","doi":"10.1016/j.zemedi.2022.05.002","DOIUrl":null,"url":null,"abstract":"<div><h3>Objectives</h3><p>To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation.</p></div><div><h3>Materials and Methods</h3><p>Single material test phantoms using a cubic lattice were designed in 3-Matic 15.0 software . Keeping the individual cubic lattice volume constant, eight different percentage ratio (R) of air: material from 0% to 70% with a 10% increment were assigned to each sample. The phantoms were printed in three materials, namely Vero PureWhite, VeroClear and TangoPlus using Polyjet technology. The CT value analysis, non-contact profile measurement and microCT-based volumetric analysis was performed for all the samples.</p></div><div><h3>Results</h3><p>The printed test phantoms produced a grey value spectrum equivalent to the radiation attenuation of human soft tissues in the range of −757 to +286 HU on CT. The results from dimensional comparison analysis of the printed phantoms with the digital test phantoms using non-contact profile measurement showed a mean accuracy of 99.07 % and that of micro-CT volumetric analysis showed mean volumetric accuracy of 84.80–94.91%. The material and printing costs of developing 24 test phantoms was 83.00 Euro.</p></div><div><h3>Conclusions</h3><p>The study shows that additive manufacturing-guided macrostructure manipulation modifies successfully the radiographic visibility of a material in CBCT imaging with 1 mm<sup>3</sup> resolution, helping customization of imaging phantoms.</p></div>","PeriodicalId":54397,"journal":{"name":"Zeitschrift fur Medizinische Physik","volume":null,"pages":null},"PeriodicalIF":2.4000,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/5d/main.PMC10311275.pdf","citationCount":"2","resultStr":"{\"title\":\"Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology\",\"authors\":\"Sepideh Hatamikia , Gunpreet Oberoi , Anna Zacher , Gernot Kronreif , Wolfgang Birkfellner , Joachim Kettenbach , Stefanie Ponti , Andrea Lorenz , Martin Buschmann , Laszlo Jaksa , Nikolaus Irnstorfer , Ewald Unger\",\"doi\":\"10.1016/j.zemedi.2022.05.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objectives</h3><p>To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation.</p></div><div><h3>Materials and Methods</h3><p>Single material test phantoms using a cubic lattice were designed in 3-Matic 15.0 software . Keeping the individual cubic lattice volume constant, eight different percentage ratio (R) of air: material from 0% to 70% with a 10% increment were assigned to each sample. The phantoms were printed in three materials, namely Vero PureWhite, VeroClear and TangoPlus using Polyjet technology. The CT value analysis, non-contact profile measurement and microCT-based volumetric analysis was performed for all the samples.</p></div><div><h3>Results</h3><p>The printed test phantoms produced a grey value spectrum equivalent to the radiation attenuation of human soft tissues in the range of −757 to +286 HU on CT. The results from dimensional comparison analysis of the printed phantoms with the digital test phantoms using non-contact profile measurement showed a mean accuracy of 99.07 % and that of micro-CT volumetric analysis showed mean volumetric accuracy of 84.80–94.91%. The material and printing costs of developing 24 test phantoms was 83.00 Euro.</p></div><div><h3>Conclusions</h3><p>The study shows that additive manufacturing-guided macrostructure manipulation modifies successfully the radiographic visibility of a material in CBCT imaging with 1 mm<sup>3</sup> resolution, helping customization of imaging phantoms.</p></div>\",\"PeriodicalId\":54397,\"journal\":{\"name\":\"Zeitschrift fur Medizinische Physik\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2023-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8b/5d/main.PMC10311275.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zeitschrift fur Medizinische Physik\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0939388922000630\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur Medizinische Physik","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0939388922000630","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
Additively manufactured test phantoms for mimicking soft tissue radiation attenuation in CBCT using Polyjet technology
Objectives
To develop and validate a simple approach for building cost-effective imaging phantoms for Cone Beam Computed Tomography (CBCT) using a modified Polyjet additive manufacturing technology where a single material can mimic a range of human soft-tissue radiation attenuation.
Materials and Methods
Single material test phantoms using a cubic lattice were designed in 3-Matic 15.0 software . Keeping the individual cubic lattice volume constant, eight different percentage ratio (R) of air: material from 0% to 70% with a 10% increment were assigned to each sample. The phantoms were printed in three materials, namely Vero PureWhite, VeroClear and TangoPlus using Polyjet technology. The CT value analysis, non-contact profile measurement and microCT-based volumetric analysis was performed for all the samples.
Results
The printed test phantoms produced a grey value spectrum equivalent to the radiation attenuation of human soft tissues in the range of −757 to +286 HU on CT. The results from dimensional comparison analysis of the printed phantoms with the digital test phantoms using non-contact profile measurement showed a mean accuracy of 99.07 % and that of micro-CT volumetric analysis showed mean volumetric accuracy of 84.80–94.91%. The material and printing costs of developing 24 test phantoms was 83.00 Euro.
Conclusions
The study shows that additive manufacturing-guided macrostructure manipulation modifies successfully the radiographic visibility of a material in CBCT imaging with 1 mm3 resolution, helping customization of imaging phantoms.
期刊介绍：
Zeitschrift fur Medizinische Physik (Journal of Medical Physics) is an official organ of the German and Austrian Society of Medical Physic and the Swiss Society of Radiobiology and Medical Physics.The Journal is a platform for basic research and practical applications of physical procedures in medical diagnostics and therapy. The articles are reviewed following international standards of peer reviewing.
Focuses of the articles are:
-Biophysical methods in radiation therapy and nuclear medicine
-Dosimetry and radiation protection
-Radiological diagnostics and quality assurance
-Modern imaging techniques, such as computed tomography, magnetic resonance imaging, positron emission tomography
-Ultrasonography diagnostics, application of laser and UV rays
-Electronic processing of biosignals
-Artificial intelligence and machine learning in medical physics
In the Journal, the latest scientific insights find their expression in the form of original articles, reviews, technical communications, and information for the clinical practice.
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