[脑少转移瘤的治疗选择:手术切除、立体定向放射外科、全脑放射治疗与联合模块在生存、功能等方面的比较]。

Harefuah Pub Date : 2023-04-01
Liat Oxman, Andrew A Kanner, Yosef Laviv
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引用次数: 0

摘要

脑转移瘤(BM)是系统性癌症患者发病和死亡的主要原因。在过去二十年中,在控制颅外疾病方面取得了巨大进步,对患者的总体生存产生了积极影响。然而,这导致寿命足够长而发展为脑转移的患者数量增加。此外,神经外科和放射治疗技术的进步使得外科切除和立体定向放射外科(SRS)成为治疗1-4脑转移患者不可或缺的一部分。这些增加的治疗可能性和治疗选择的组合,如手术切除、SRS、全脑放射治疗(WBRT)和最近的靶向分子治疗,导致了大量但有时令人困惑的已发表数据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[THERAPEUTIC OPTIONS FOR BRAIN OLIGOMETASTASES: COMPARISON BETWEEN SURGICAL RESECTION, STEREOTACTIC RADIOSURGERY, WHOLE BRAIN RADIATION THERAPY AND COMBINED MODULES IN RELATION TO SURVIVAL, FUNCTION AND OTHER CONSIDERATIONS].

Introduction: Brain metastases (BM) are a leading cause of morbidity and mortality in patients with systemic cancer. In the last two decades, an enormous improvement in controlling extra-cranial disease has been achieved, positively affecting the overall survival of patients. However, this has led to an increased number of patients who live long enough to develop BM. In addition, technological improvements in neurosurgery and radiotherapy caused both surgical resection and stereotactic radiosurgery (SRS) to become an integral part of the armamentarium when treating a patient with 1-4 BM. These increased therapeutic possibilities and combination of therapeutic options such as surgical resection, SRS, whole brain radiation therapy (WBRT) and lately targeted molecular therapy, have led to an enormous amount of, yet sometimes confusing, published data.

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