白芨(Bletilla striata)的代谢物化学成分Reichb。f.内生真菌:草青霉。

IF 1.6 4区生物学 Q2 AGRONOMY

Mycobiology Pub Date : 2023-01-01 DOI:10.1080/12298093.2023.2216944

Ran Liu, Xuehua Han, Jing Gao, Min Luo, Dale Guo, Guangzhi Wang

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引用次数: 0

摘要

草酸青霉可以从白芨(Bletilla striata, Thunb)中分离得到。Reichb。f .块茎。其固态发酵产物采用渗透萃取法浓缩。采用制备高效液相色谱法对乙酸乙酯提取物进行分离纯化。基于光谱法的使用,我们已经确定17个已知化合物,12日13-dihydroxy-fumitremorgin C (1) pseurotin(2),酪醇(3),三轮车——(L-Pro-L-Val) (4), cis-4-hydroxy-8-O-methylmellein(5),尿嘧啶(6),三轮车——(L-Pro-L-Ala) (7), 1, 2, 3, 4-tetrahydro-4-hydroxy-4-quinolin羧酸(8),三轮车——(Gly-L-Pro)(9), 2的脱氧尿苷(10),1 -(β-D-ribofuranosyl)胸腺嘧啶(11),三轮车——(L-Val-Gly)(12), 2》脱氧胸苷(13),三轮车——(Gly-D-Phe) (14), cyclo-L——(4-hydroxyprolinyl) -D-leucine (15),三轮车- (L) 4-hydroxy-pro (L)板式换热器(16),尿苷(17)。本文报道了化合物1-3、5、7-8、11-12、14-17首次从该内生菌中分离得到。

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Metabolite Chemical Composition of the Bletilla striata (Thunb.) Reichb. f. Endophyte Penicillium oxalicum.

Penicillium oxalicum strain can be isolated from the Bletilla striata (Thunb.) Reichb. f. tubers. Its solid-state fermentation products are concentrated by percolation extraction. Separation and purification have been conducted to the ethyl acetate extracts by preparative HPLC. Based on the use of spectrometry, we have determined 17 known compounds, 12,13-dihydroxy-fumitremorgin C (1), pseurotin A (2), tyrosol (3), cyclo-(L-Pro-L-Val) (4), cis-4-hydroxy-8-O-methylmellein (5), uracil (6), cyclo-(L-Pro-L-Ala) (7), 1,2,3,4-tetrahydro-4-hydroxy-4-quinolin carboxylic acid (8), cyclo-(Gly-L-Pro) (9), 2'-deoxyuridine (10), 1-(β-D-ribofuranosyl)thymine (11), cyclo-(L-Val-Gly) (12), 2'-deoxythymidine (13), cyclo-(Gly-D-Phe) (14), cyclo-L-(4-hydroxyprolinyl)-D-leucine (15), cyclo-(L)-4-hydroxy-Pro-(L)-Phe (16), uridine (17). Here, we report compounds 1-3, 5, 7-8, 11-12, 14-17 are first found and isolated from this endophyte.

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来源期刊

Mycobiology AGRONOMYMYCOLOGY-MYCOLOGY

CiteScore

3.90

自引率

5.30%

发文量

审稿时长

22 weeks

期刊介绍： Mycobiology is an international journal devoted to the publication of fundamental and applied investigations on all aspects of mycology and their traditional allies. It is published quarterly and is the official publication of the Korean Society of Mycology. Mycobiology publishes reports of basic research on fungi and fungus-like organisms, including yeasts, filamentous fungi, lichen fungi, oomycetes, moulds, and mushroom. Topics also include molecular and cellular biology, biochemistry, metabolism, developmental biology, environmental mycology, evolution, ecology, taxonomy and systematics, genetics/genomics, fungal pathogen and disease control, physiology, and industrial biotechnology using fungi.