白细胞中 Y 染色体的马赛克缺失：对男性健康的影响

IF 5.3 2区医学 Q1 PHYSIOLOGY

Physiology Pub Date : 2023-07-01 Epub Date: 2023-03-28 DOI:10.1152/physiol.00008.2023

Soichi Sano, Mark C Thel, Kenneth Walsh

引用次数: 0

摘要

我们简要介绍了血液中的 Y 染色体缺失（LOY），并描述了这种情况的已知风险因素。然后，我们概述了 LOY 与年龄相关疾病特征之间的关联。最后，我们讨论了小鼠模型和 LOY 导致疾病的潜在机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Mosaic Loss of Y Chromosome in White Blood Cells: Its Impact on Men's Health.

We present a brief introduction of loss of Y chromosome (LOY) in blood and describe the known risk factors for this condition. We then overview the associations between LOY and age-related disease traits. Finally, we discuss murine models and the potential mechanisms by which LOY contributes to disease.

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来源期刊

Physiology 医学-生理学

CiteScore

14.50

自引率

0.00%

发文量

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