Stalin Vilcarromero, Max Small, Alexis Lizarzaburu, Abel Rivadeneyra-Rodriguez
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引用次数: 0
摘要
本病例是一名免疫功能正常的年轻患者,曾患肺结核,因持续发热、体重减轻、呼吸困难和水泡样杂音消失的亚急性临床表现就诊。胸部 CT 扫描显示左胸腔有广泛的空洞。采集了样本以检测常见病菌。随后,放置了胸腔引流管,并开始了抗生素治疗。MALDI-TOF MS 检测发现了一种厌氧菌 Parvimonas micra,它是口腔菌群的共生菌,与严重的牙周炎有关,但很少在胸腔积液病例中出现,尤其是在免疫功能正常的患者中。在口腔评估时,确诊患者患有牙龈炎和第三磨牙冠周炎。患者病情进展良好。在亚急性或慢性胸膜腔积液病例中,除分枝杆菌外,还应将小伞菌视为可能的病原体。在这些病例中,应考虑进行 MALDI-TOF MS 或 16S rRNA 测序、胸腔置管、经验性抗生素治疗和充分的口腔评估等检查。
Pleural empyema by Parvimonas micra in an immunocompetent patient: a case report.
We present the case of a young immunocompetent patient, with a history of pulmonary tuberculosis, who attended the hospital with a subacute clinical picture of persistent fever, weight loss, dyspnea and abolition of vesicular murmur. Chest CT scan showed an extensive empyema in the left hemithorax. Samples were taken for detection of common germs. Then, a chest drainage tube was placed and antibiotic therapy started. The MALDI-TOF MS test identified Parvimonas micra, an anaerobic bacterium, commensal to the oral flora, associated with severe periodontitis, but rarely reported in cases of pleural empyema, especially in immunocompetent patients. Gingivitis and pericoronaritis of the third molar were diagnosed during oral evaluation. The patient progressed favorably. Parvimonas micra should be considered as a possible etiological agent in cases of subacute or chronic pleural empyema, in addition to mycobacteria. Tests such as MALDI-TOF MS or 16S rRNA sequencing, chest tube placement, empirical antibiotic coverage and an adequate oral evaluation should be considered in these cases.
期刊介绍:
La Revista Peruana de Medicina Experimental y Salud Pública (RPMESP) es el órgano oficial de difusión científica del Instituto Nacional de Salud (INS) del Perú. Es una publicación arbitrada por pares, de periodicidad trimestral, de ámbito y difusión mundial, indizada en MEDLINE/Index Medicos, SCOPUS, EMBASE, SciELO Salud Pública y otras bases de datos internacionales. La RPMESP es distribuida en su versión impresa y electrónica, con acceso gratuito a texto completo. La RPMESP publica artículos referidos a temas del ámbito biomédico y de salud pública, resaltando aportes prácticos, que contribuyan a mejorar la situación de salud del país y de la región. Propicia el intercambio de la experiencia científica en salud entre instituciones y personas dedicadas a la investigación dentro y fuera del Perú a fin de promover el avance y la aplicación de la investigación en salud.