实验室生物标志物在囊性纤维化变应性支气管肺曲霉病诊断和治疗随访中的应用。

IF 6.6 2区医学 Q1 MEDICAL LABORATORY TECHNOLOGY

Critical reviews in clinical laboratory sciences Pub Date : 2023-01-01 DOI:10.1080/10408363.2022.2101612

Sophie Steels, Marijke Proesmans, Xavier Bossuyt, Lieven Dupont, Glynis Frans

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引用次数: 0

摘要

过敏性支气管肺曲霉病(ABPA)是一种严重的炎症性呼吸道疾病，是由对烟曲霉定植气道的超敏反应引起的。最常见于哮喘或囊性纤维化患者。ABPA的诊断是基于临床、放射学和免疫学结果的结合，这些结果已包括在多年来的不同诊断标准中。本文就这些诊断标准中包含的生物标志物以及可能用于囊性纤维化ABPA诊断和治疗随访的新研究生物标志物进行综述。

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Laboratory biomarkers in the diagnosis and follow-up of treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis.

Allergic bronchopulmonary aspergillosis (ABPA), a severe inflammatory respiratory disease, is caused by a hypersensitivity reaction to the colonization of the airways with Aspergillus fumigatus. It is most often described in patients with asthma or cystic fibrosis. The diagnosis of ABPA is based on a combination of clinical, radiological, and immunological findings that have been included in different diagnostic criteria over the years. In this paper, we review the biomarkers included in these diagnostic criteria and novel research biomarkers that may be used in the diagnosis and treatment follow-up of ABPA in cystic fibrosis.

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来源期刊

Critical reviews in clinical laboratory sciences 医学-医学实验技术

CiteScore

20.00

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Critical Reviews in Clinical Laboratory Sciences publishes comprehensive and high quality review articles in all areas of clinical laboratory science, including clinical biochemistry, hematology, microbiology, pathology, transfusion medicine, genetics, immunology and molecular diagnostics. The reviews critically evaluate the status of current issues in the selected areas, with a focus on clinical laboratory diagnostics and latest advances. The adjective “critical” implies a balanced synthesis of results and conclusions that are frequently contradictory and controversial.