炎症性肠病与大麻:关键咨询策略。

IF 2.6 3区 医学 Q2 GASTROENTEROLOGY & HEPATOLOGY
Current Opinion in Gastroenterology Pub Date : 2023-07-01 Epub Date: 2023-05-03 DOI:10.1097/MOG.0000000000000946
Jakob Saidman, Samantha Rubin, Arun Swaminath
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引用次数: 0

摘要

综述目的:在炎症性肠病(IBD)患者中,大麻的使用越来越频繁。由于大麻使用量的增加,胃肠病学家需要认识到在IBD患者群体中使用大麻的益处和风险。最近的发现:最近的研究试图确定大麻是否可以改善炎症性肠病患者的炎症生物标志物或内镜检查结果,但结果尚未确定。然而,大麻已被证明对IBD患者的症状和生活质量有影响。尽管有这些好处,但在IBD中使用大麻并非没有风险,包括潜在的系统性疾病、毒素摄入和严重的药物相互作用。摘要:在这篇综述文章中,我们使用基于案例的方法来讨论关键的临床数据,这些数据告诉我们在IBD中使用大麻的益处和风险。内源性大麻素系统在调节包括胃肠道在内的各种生理功能方面发挥着至关重要的作用。研究调查了大麻对包括IBD在内的各种疾病的影响。临床医生必须了解最新数据,以便正确地教育患者使用该药物的益处和风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Inflammatory bowel disease and cannabis: key counseling strategies.

Purpose of review: Cannabis use is becoming more frequent in patients with inflammatory bowel disease (IBD). Because of the increased usage, gastroenterologists need to be cognizant of the benefits and risks associated with cannabis use in the IBD-patient population.

Recent findings: Recent studies have attempted to determine whether cannabis can improve biomarkers or endoscopic findings of inflammation in patients with IBD, but the results have been inconclusive. However, cannabis has been shown to have an impact on the symptoms and quality of life of individuals with IBD. Despite these benefits, the use of cannabis in IBD is not without risks, including the potential for systemic illness, toxin ingestion and significant drug interactions.

Summary: In this review article, we use a case-based approach to discuss the critical clinical data that informs us of the benefits and risks of cannabis use in IBD. The endocannabinoid system plays a crucial role in regulating various physiological functions including the gastrointestinal tract. Studies have investigated the impact of cannabis on various medical conditions, including IBD. Clinicians must be aware of the most recent data to properly educate their patients on the benefits and risks of its use.

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来源期刊
Current Opinion in Gastroenterology
Current Opinion in Gastroenterology 医学-胃肠肝病学
CiteScore
5.30
自引率
0.00%
发文量
137
审稿时长
6-12 weeks
期刊介绍: ​​​​​​​Published bimonthly and offering a unique and wide ranging perspective on the key developments in the field, each issue of Current Opinion in Gastroenterology features hand-picked review articles from our team of expert editors. With twelve disciplines published across the year – including gastrointestinal infections, nutrition and inflammatory bowel disease – every issue also contains annotated references detailing the merits of the most important papers.
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