修改静脉流出避免胰腺移植血栓性移植物衰竭。

IF 1.1 4区 医学 Q3 SURGERY
Je Ho Ryu, Jae Ryong Shim, Tae Beom Lee, Kwangho Yang, Taeun Kim, Seo Rin Kim, Byunghyun Choi
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引用次数: 0

摘要

即使根据最近的数据,仍有5-10%的胰腺移植经历早期技术失败。移植物血栓形成是早期技术失败的主要原因,即使只使用最佳移植物,就像韩国的情况一样。本研究的目的是确定我们是否可以通过改变静脉流出来避免血栓性移植物衰竭。材料与方法2017年3月至2021年12月,共进行59例胰腺移植。截至2019年5月,采用尸体腔静脉围血管成形术移植门静脉31例(腔静脉组)。从那时起,总共进行了28例主动脉间置移植物来移植门静脉(主动脉组)。结果两组患者的基线特征无显著差异。每组有1例技术故障。早期移植失败率分别为3.2%和3.4% (P=1.000), 1年移植存活率分别为96.8%和94.4% (P=0.991)。尽管在腔静脉组发生了移植物威胁血栓形成,但两组均未发生血栓性移植物衰竭,尽管减少了(腔静脉组)或不使用肝素(主动脉组)。结论:当采用最佳移植物时,两种改变静脉流出的技术均可显著减少血栓性移植物衰竭。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation.

Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation.

Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation.

Modification of Venous Outflow to Avoid Thrombotic Graft Failure in Pancreas Transplantation.

BACKGROUND Even with recent data, 5-10% of pancreas transplants experience early technical failure. Graft thrombosis is the primary cause of early technical failure, even when only optimal grafts are used, as is the case in Korea. The purpose of this study was to determine whether we can avoid thrombotic graft failure by modifying venous outflow. MATERIAL AND METHODS Between March 2017 and December 2021, a total of 59 pancreas transplantations were performed. Until May 2019, 31 cases of fence-angioplasty with cadaveric vena cava were performed to graft portal veins (the vena cava group). Since then, a total of 28 aortic interposition grafts have been performed to graft portal veins (the aortic group). RESULTS Between the 2 groups, there was no significant difference in baseline characteristics. Each group had 1 instance of technical failure. Early graft failure rates were 3.2% and 3.4%, respectively (P=1.000), while 1-year graft survival rates were 96.8% and 94.4%, respectively (P=0.991). Although a graft-threatening thrombosis occurred in the vena cava group, neither group experienced thrombotic graft failure, despite the decreased (vena cava group) or absence of heparin use (aorta group). CONCLUSIONS When the optimal graft is used, both techniques of modifying venous outflow can significantly reduce thrombotic graft failure.

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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
79
审稿时长
>12 weeks
期刊介绍: Annals of Transplantation is one of the fast-developing journals open to all scientists and fields of transplant medicine and related research. The journal is published quarterly and provides extensive coverage of the most important advances in transplantation. Using an electronic on-line submission and peer review tracking system, Annals of Transplantation is committed to rapid review and publication. The average time to first decision is around 3-4 weeks. Time to publication of accepted manuscripts continues to be shortened, with the Editorial team committed to a goal of 3 months from acceptance to publication. Expert reseachers and clinicians from around the world contribute original Articles, Review Papers, Case Reports and Special Reports in every pertinent specialty, providing a lot of arguments for discussion of exciting developments and controversies in the field.
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