Xiaoyu Peng, Jordan L Hickman, Spencer G Bowles, Dane C Donegan, Cristin G Welle
{"title":"电刺激创新利用神经可塑性恢复运动功能。","authors":"Xiaoyu Peng, Jordan L Hickman, Spencer G Bowles, Dane C Donegan, Cristin G Welle","doi":"10.2217/bem-2019-0002","DOIUrl":null,"url":null,"abstract":"<p><p>Novel technology and innovative stimulation paradigms allow for unprecedented spatiotemporal precision and closed-loop implementation of neurostimulation systems. In turn, precise, closed-loop neurostimulation appears to preferentially drive neural plasticity in motor networks, promoting neural repair. Recent clinical studies demonstrate that electrical stimulation can drive neural plasticity in damaged motor circuits, leading to meaningful improvement in users. Future advances in these areas hold promise for the treatment of a wide range of motor systems disorders.</p>","PeriodicalId":72364,"journal":{"name":"Bioelectronics in medicine","volume":"1 4","pages":"251-263"},"PeriodicalIF":0.0000,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046169/pdf/nihms-1048067.pdf","citationCount":"0","resultStr":"{\"title\":\"Innovations in electrical stimulation harness neural plasticity to restore motor function.\",\"authors\":\"Xiaoyu Peng, Jordan L Hickman, Spencer G Bowles, Dane C Donegan, Cristin G Welle\",\"doi\":\"10.2217/bem-2019-0002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Novel technology and innovative stimulation paradigms allow for unprecedented spatiotemporal precision and closed-loop implementation of neurostimulation systems. In turn, precise, closed-loop neurostimulation appears to preferentially drive neural plasticity in motor networks, promoting neural repair. Recent clinical studies demonstrate that electrical stimulation can drive neural plasticity in damaged motor circuits, leading to meaningful improvement in users. Future advances in these areas hold promise for the treatment of a wide range of motor systems disorders.</p>\",\"PeriodicalId\":72364,\"journal\":{\"name\":\"Bioelectronics in medicine\",\"volume\":\"1 4\",\"pages\":\"251-263\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8046169/pdf/nihms-1048067.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioelectronics in medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2217/bem-2019-0002\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2019/4/24 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioelectronics in medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/bem-2019-0002","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2019/4/24 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
Innovations in electrical stimulation harness neural plasticity to restore motor function.
Novel technology and innovative stimulation paradigms allow for unprecedented spatiotemporal precision and closed-loop implementation of neurostimulation systems. In turn, precise, closed-loop neurostimulation appears to preferentially drive neural plasticity in motor networks, promoting neural repair. Recent clinical studies demonstrate that electrical stimulation can drive neural plasticity in damaged motor circuits, leading to meaningful improvement in users. Future advances in these areas hold promise for the treatment of a wide range of motor systems disorders.