Jorge Aróstegui Aguilar, Leire Loidi, Ingrid Hiltun, Mónica Larrea, Lourdes Cascante, Juan Ignacio Yanguas
{"title":"[小儿生殖器硬化性地衣:11例女孩]。","authors":"Jorge Aróstegui Aguilar, Leire Loidi, Ingrid Hiltun, Mónica Larrea, Lourdes Cascante, Juan Ignacio Yanguas","doi":"10.23938/ASSN.1014","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls.</p><p><strong>Methods: </strong>Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022.</p><p><strong>Results: </strong>Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical cortico-steroids achieved a good partial response, without complete remission of the lesions.</p><p><strong>Conclusion: </strong>Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding ireversible genital structural alteration.</p>","PeriodicalId":7775,"journal":{"name":"Anales Del Sistema Sanitario De Navarra","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2022-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/d3/assn-45-03-e1014.PMC10065031.pdf","citationCount":"0","resultStr":"{\"title\":\"[Pediatric genital lichen sclerosus: a case series of 11 girls].\",\"authors\":\"Jorge Aróstegui Aguilar, Leire Loidi, Ingrid Hiltun, Mónica Larrea, Lourdes Cascante, Juan Ignacio Yanguas\",\"doi\":\"10.23938/ASSN.1014\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls.</p><p><strong>Methods: </strong>Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022.</p><p><strong>Results: </strong>Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical cortico-steroids achieved a good partial response, without complete remission of the lesions.</p><p><strong>Conclusion: </strong>Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding ireversible genital structural alteration.</p>\",\"PeriodicalId\":7775,\"journal\":{\"name\":\"Anales Del Sistema Sanitario De Navarra\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2022-11-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/96/d3/assn-45-03-e1014.PMC10065031.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Anales Del Sistema Sanitario De Navarra\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.23938/ASSN.1014\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Anales Del Sistema Sanitario De Navarra","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.23938/ASSN.1014","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
[Pediatric genital lichen sclerosus: a case series of 11 girls].
Background: Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls.
Methods: Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022.
Results: Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical cortico-steroids achieved a good partial response, without complete remission of the lesions.
Conclusion: Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding ireversible genital structural alteration.
期刊介绍：
La revista Anales del Sistema Sanitario de Navarra es una revista de contenido médico sanitario de carácter generalista. En ella tienen cabida artículos referidos a temas de salud/enfermedad en general, salud pública, administración y gestión sanitaria y Atención Primaria de salud.
![[Pediatric genital lichen sclerosus: a case series of 11 girls].](https://img.booksci.cn/booksciimg/2022-11/2023111578214553803056535571203.jpg)
![[Pediatric genital lichen sclerosus: a case series of 11 girls].](https://img.booksci.cn/booksciimg/2022-11/2023111578288806104941789823495.jpg)
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