儿童间皮瘤。

IF 8.3 2区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

ACS Applied Materials & Interfaces Pub Date : 2023-07-01 Epub Date: 2023-05-22 DOI:10.1097/PAP.0000000000000403

Eduardo Zambrano, Andrés Matoso, Miguel Reyes-Múgica

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引用次数: 0

摘要

间皮瘤是一种罕见的侵袭性肿瘤，起源于间皮细胞。尽管极为罕见，但这些肿瘤可能发生在儿童身上。然而，与成人间皮瘤不同的是，环境暴露，特别是石棉暴露，似乎在儿童间皮瘤中没有发挥主要作用，近年来已经发现了导致这些肿瘤的特定基因重排。这些分子改变可能在未来为靶向治疗提供越来越多的机会，这可能为这些高度侵袭性的恶性肿瘤提供更好的结果。

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Mesotheliomas in Children.

Mesotheliomas are rare and aggressive tumors that originate from mesothelial cells. Although exceedingly rare, these tumors may occur in children. Different from adult mesotheliomas, however, environmental exposures particularly to asbestos do not appear to play a major role in mesotheliomas in children, in whom specific genetic rearrangements driving these tumors have been identified in recent years. These molecular alterations may increasingly offer opportunities for targeted therapies in the future, which may provide better outcomes for these highly aggressive malignant neoplasms.

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来源期刊

ACS Applied Materials & Interfaces 工程技术-材料科学：综合

CiteScore

16.00

自引率

6.30%

发文量

4978

审稿时长

1.8 months

期刊介绍： ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.