量子噪声可能限制脊椎动物身体平面图左右组织中纤毛的机械感觉敏感性

IF 3.2 3区生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY

Progress in Biophysics & Molecular Biology Pub Date : 2023-07-01 DOI:10.1016/j.pbiomolbio.2023.04.010

Julyan H.E. Cartwright

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引用次数: 0

摘要

大自然会利用纤毛中的量子力学来优化脊椎动物发育过程中左右对称性断裂机制的敏感性吗？我评估了机械感应——即通过机械刺激感觉纤毛检测左右不对称信号，而不是生物化学信号——是否可能通过量子力学在脊椎动物身体计划的胚胎左右组织者中发挥作用。我的结论是，量子生物学在纤毛的机械感应中可能发挥作用。该系统可能不受经典热噪声的限制，而是受量子噪声的限制。

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Quantum noise may limit the mechanosensory sensitivity of cilia in the left–right organizer of the vertebrate bodyplan

Could nature be harnessing quantum mechanics in cilia to optimize the sensitivity of the mechanism of left–right symmetry breaking during development in vertebrates? I evaluate whether mechanosensing — i.e., the detection of a left-right asymmetric signal through mechanical stimulation of sensory cilia, as opposed to biochemical signalling — might be functioning in the embryonic left–right organizer of the vertebrate bodyplan through quantum mechanics. I conclude that there is a possible role for quantum biology in mechanosensing in cilia. The system may not be limited by classical thermal noise, but instead by quantum noise, with an amplification process providing active cooling.

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来源期刊

Progress in Biophysics & Molecular Biology 生物-生化与分子生物学

CiteScore

8.60

自引率

7.90%

发文量

审稿时长

85 days

期刊介绍： Progress in Biophysics & Molecular Biology is an international review journal and covers the ground between the physical and biological sciences since its launch in 1950. It indicates to the physicist the great variety of unsolved problems awaiting attention in biology and medicine. The biologist and biochemist will find that this journal presents new and stimulating ideas and novel approaches to studying and influencing structural and functional properties of the living organism. This journal will be of particular interest to biophysicists, biologists, biochemists, cell physiologists, systems biologists, and molecular biologists.