死亡患者的膝下和膝上截肢与人口学、合并症和血液学参数的比较。

IF 2.5 3区 医学 Q1 ORTHOPEDICS
Cafer Özgür Hançerli, Necati Doğan
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引用次数: 0

摘要

背景:本研究旨在通过比较接受膝下和膝上截肢并在随访期间死亡的患者的人口学数据、合并症因素和血液学值,建立对死亡率有较高贡献的死亡率预测参数。材料和方法:2014年3月至2022年1月,回顾性评估单个中心122例因慢性糖尿病而发生足坏疽并行膝下或膝上截肢的患者。术后自然死亡的患者也被纳入研究。在膝盖以下截肢的人被分配到第一组,在膝盖以上截肢的人被分配到第二组。比较两组患者的年龄、性别、截肢部位、合并症、美国麻醉学会(ASA)评分、Charlson合并症指数(CCI)、死亡时间、首次入院时血液学指标,并进行统计学分析。结果:组1 (n = 50)与组2 (n = 37)在年龄、性别、手术部位、合并症数、CCI等方面分布相似(p > 0.05)。2组患者ASA评分及c反应蛋白(CRP)水平均高于1组,差异有统计学意义(p 0.05)。结论:高ASA评分、低白蛋白值和高CRP值是高死亡率的重要预测因子。肌酐水平和HbA1c值在预测死亡率方面相当无效。证据等级:3级,回顾性比较研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison of below-knee and above-knee amputations with demographic, comorbidity, and haematological parameters in patients who died.

Background: This study aimed to establish mortality predictive parameters with a higher contribution to mortality by comparing the demographic data, comorbid factors, and haematological values of patients who underwent below-knee and above-knee amputation and had died during the follow-up period.

Materials and methods: Between March 2014 and January 2022, 122 patients in a single centre who developed foot gangrene due to chronic diabetes and underwent below-knee or above-knee amputation were evaluated retrospectively. Patients who died of natural causes during the post-operative period were included in the study. Those who were amputated below the knee were assigned to Group 1, and those who were amputated above the knee were assigned to Group 2. The patients' age, gender, side of amputation, comorbid diseases, American Society of Anaesthesiologists (ASA) score, Charlson comorbidity index (CCI), death time, and haematological values at the time of first admission were compared between the two groups and statistical analyses were performed.

Results: Group 1 (n = 50) and Group 2 (n = 37) had similar distributions in terms of age, gender, side of operation, number of comorbidities, and CCI (p > 0.05). Group 2's mean ASA score and c-reactive protein (CRP) levels were statistically higher than those of Group 1 (p < 0.05). Death time, albumin value, and HbA1c levels were statistically lower in Group 2 than in Group 1 (p < 0.05). There were no significant differences between the groups in haemogram, white blood cells (WBC), lymphocytes, neutrophils, creatinine, and Na values at the time of first admission (p > 0.05).

Conclusion: A high ASA score, low albumin value, and high CRP value were significant predictors of high mortality. Creatinine levels and HbA1c values were quite ineffective in predicting mortality.

Level of evidence: Level 3, retrospective comparative study.

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来源期刊
CiteScore
4.50
自引率
10.30%
发文量
83
审稿时长
>12 weeks
期刊介绍: Journal of Foot and Ankle Research, the official journal of the Australian Podiatry Association and The College of Podiatry (UK), is an open access journal that encompasses all aspects of policy, organisation, delivery and clinical practice related to the assessment, diagnosis, prevention and management of foot and ankle disorders. Journal of Foot and Ankle Research covers a wide range of clinical subject areas, including diabetology, paediatrics, sports medicine, gerontology and geriatrics, foot surgery, physical therapy, dermatology, wound management, radiology, biomechanics and bioengineering, orthotics and prosthetics, as well the broad areas of epidemiology, policy, organisation and delivery of services related to foot and ankle care. The journal encourages submissions from all health professionals who manage lower limb conditions, including podiatrists, nurses, physical therapists and physiotherapists, orthopaedists, manual therapists, medical specialists and general medical practitioners, as well as health service researchers concerned with foot and ankle care. The Australian Podiatry Association and the College of Podiatry (UK) have reserve funds to cover the article-processing charge for manuscripts submitted by its members. Society members can email the appropriate contact at Australian Podiatry Association or The College of Podiatry to obtain the corresponding code to enter on submission.
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