波兰慢性伤口感染的病原菌分离。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Marcin Malka, Arkadiusz Krakowiecki, Magdalena Chojak, Marek Pławski, Mariusz Wądołek, Agnieszka Wołowicz, Aleksandra Dyczewska, Aleksandra Paź, Katarzyna Pawlik, Tomasz Grzela
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引用次数: 0

摘要

慢性伤口感染是阻碍或阻止伤口愈合的因素之一。感染的发生率可能因伤口的类型而异。据估计,高达30%的糖尿病足综合征患者发生有临床意义的感染。准确诊断感染特征和适当的微生物试验对于引入适当的局部治疗和通常的全身治疗至关重要。该研究的目的是对2013-2021年在伤口护理中心门诊咨询的波兰患者感染慢性伤口中发现的微生物群进行比较分析。微生物培养试验的指征是发现局部感染迹象,取样前进行适当的伤口清创。标准培养技术是深层组织活检。该研究的材料来自1199名患者。总的来说,3917个微生物试验结果进行了回顾性分析。本文以培养微生物的数量及其相对发生率为百分比的形式提出结果,考虑到从伤口获得材料的类型的划分。分析组中最常见的分离微生物为金黄色葡萄球菌(该组14.3%为MRSA -耐甲氧西林金黄色葡萄球菌)和粪肠球菌(该组2.4%为VRE -耐万古霉素肠球菌)。对如此广泛的数据库进行进一步分析,特别是对分离微生物的药物敏感性进行进一步分析,似乎对于制定感染性慢性伤口经验性抗菌治疗的新建议至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

The Pathogen Isolates in Chronic Wound Infections in Poland.

The Pathogen Isolates in Chronic Wound Infections in Poland.

The Pathogen Isolates in Chronic Wound Infections in Poland.

The Pathogen Isolates in Chronic Wound Infections in Poland.

Chronic wound infection is one of the factors that hinder or prevent its healing. The incidence of infection may vary depending on the type of wound. It is estimated that clinically significant infection in diabetic foot syndrome occurs in up to 30% of patients. Accurate diagnosis of infection features and proper microbiological tests are crucial for introducing of appropriate local and often systemic treatment. The aim of the study was a comparative analysis of the microbiota found in infected chronic wounds in patients from Poland, consulted on an outpatient basis at a wound care center in 2013-2021. The indication for microbiology culture tests was the detection of local signs of infection, and sampling was preceded by appropriate wound debridement. The standard culture technique was a deep-tissue biopsy. Material for the study was collected from 1,199 patients. Overall, 3,917 results of microbiological tests were subjected to retrospective analysis. The paper presents the results in the form of the number of cultured microorganisms and their relative incidence as percentages, considering the division into the types of wounds from which the material was obtained. The most frequently isolated microorganisms in the analyzed group were Staphylococcus aureus (14.3% of this group were MRSA - methicillin-resistant Staphylococcus aureus) and Enterococcus faecalis (2.4% of this group were VRE - vancomycin-resistant Enterococcus). Further analysis of such an extensive database, especially regarding drug susceptibility of isolated microorganisms, seems crucial to elaborate new recommendations for empirical antibacterial treatment of infected chronic wounds.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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