向淋巴系统输送生理学知情药物的纳米技术。

IF 12.8 1区工程技术 Q1 ENGINEERING, BIOMEDICAL

Annual Review of Biomedical Engineering Pub Date : 2023-06-08 Epub Date: 2023-03-31 DOI:10.1146/annurev-bioeng-092222-034906

Katharina Maisel, Claire A McClain, Amanda Bogseth, Susan N Thomas

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引用次数: 0

摘要

伴随着免疫治疗策略对治疗和预防疾病的转化影响越来越大，生物科学和生物工程对淋巴系统的兴趣也越来越大。本文介绍了淋巴系统的生理学，从其组织结构到免疫功能和作用。还阐述了在基于纳米颗粒的药物递送应用中分析和操作该组织系统的设计原理和工程方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Nanotechnologies for Physiology-Informed Drug Delivery to the Lymphatic System.

Accompanying the increasing translational impact of immunotherapeutic strategies to treat and prevent disease has been a broadening interest across both bioscience and bioengineering in the lymphatic system. Herein, the lymphatic system physiology, ranging from its tissue structures to immune functions and effects, is described. Design principles and engineering approaches to analyze and manipulate this tissue system in nanoparticle-based drug delivery applications are also elaborated.

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来源期刊

Annual Review of Biomedical Engineering 工程技术-工程：生物医学

CiteScore

18.80

自引率

0.00%

发文量

期刊介绍： Since 1999, the Annual Review of Biomedical Engineering has been capturing major advancements in the expansive realm of biomedical engineering. Encompassing biomechanics, biomaterials, computational genomics and proteomics, tissue engineering, biomonitoring, healthcare engineering, drug delivery, bioelectrical engineering, biochemical engineering, and biomedical imaging, the journal remains a vital resource. The current volume has transitioned from gated to open access through Annual Reviews' Subscribe to Open program, with all articles published under a CC BY license.